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      Single-particle tracking: applications to membrane dynamics.

      Annual review of biophysics and biomolecular structure

      methods, Microscopy, Video, metabolism, Membrane Proteins, Membrane Lipids, physiology, Membrane Fluidity, Humans, Diffusion

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          Abstract

          Measurements of trajectories of individual proteins or lipids in the plasma membrane of cells show a variety of types of motion. Brownian motion is observed, but many of the particles undergo non-Brownian motion, including directed motion, confined motion, and anomalous diffusion. The variety of motion leads to significant effects on the kinetics of reactions among membrane-bound species and requires a revision of existing views of membrane structure and dynamics.

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          Journal
          9241424
          10.1146/annurev.biophys.26.1.373

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