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      Optical coherence tomography (OCT) angiolytics: a review of OCT angiography quantitative biomarkers.

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          Abstract

          Optical coherence tomography angiography (OCTA) provides a non-invasive method to obtain angiography of the chorioretinal vasculature leading to its recent widespread adoption. With a growing number of studies exploring the use of OCTA, various biomarkers quantifying the vascular characteristics have come to light. In the current report, we summarize the biomarkers currently described for retinal and choroidal vasculature using OCTA systems and the methods used to obtain them. Further, we present a critical review of these methods and key findings in common retinal diseases and appraise future directions, including applications of artificial intelligence in OCTA .

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          Author and article information

          Journal
          Surv Ophthalmol
          Survey of ophthalmology
          Elsevier BV
          1879-3304
          0039-6257
          Nov 05 2021
          Affiliations
          [1 ] Cole Eye Institute, Cleveland Clinic, Cleveland, OH, USA; Government Medical College and Hospital, Chandigarh, India.
          [2 ] Institut Clinic d'Oftalmologia (ICOF) Hospital Clinic, Barcelona, Spain; Institut de Investigacions Biomediques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.
          [3 ] Government Medical College and Hospital, Chandigarh, India.
          [4 ] Department of Surgical and Biomedical Sciences, University of Perugia, S.Maria della Misericordia Hospital, Perugia, Italy.
          [5 ] University of Pittsburgh Medical Center Eye Center, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address: jay.chhablani@gmail.com.
          Article
          S0039-6257(21)00193-4
          10.1016/j.survophthal.2021.11.002
          34748794
          1ae8140d-f959-431b-b69d-bafb32ef2720
          Copyright © 2021 Elsevier Inc. All rights reserved.
          History

          Vascular biomarkers,Optical coherence tomography angiography,OCTA,Chorioretinal vasculature,Quantitative biomarkers

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