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      Effectiveness of a brief psychotherapeutic intervention compared with treatment as usual for adolescent nonsuicidal self-injury: a single-centre, randomised controlled trial

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          Abstract

          Although nonsuicidal self-injury (NSSI) is a clinically significant behavior, evidence-based, specific, time-, and cost-effective treatment approaches are lacking. The aim of this study was to compare the efficacies of a brief cognitive-behavioral psychotherapy manual, the Cutting Down Programme (CDP), and treatment as usual (TAU) in the treatment of adolescent NSSI. We conducted a single-centre randomised controlled trial (RCT). Eligible participants were aged 12–17 years engaging in repetitive NSSI (at least 5 times within the past 6 months). We randomly allocated 74 participants to CDP ( n = 37) or TAU ( n = 37; in a 1:1 ratio). Outcome measures were administered before treatment (T0), directly after CDP or 4 months after baseline evaluation in the TAU group (T1), and another 6 months later (T2; primary endpoint). Primary outcome was a 50% reduction in NSSI frequency within the past 6 months at 10-month follow-up (T2). Regarding the primary outcome, there were no significant differences between the CDP ( n = 26; 70.3%) and TAU group [ n = 27; 73.0%; χ 2(1) = 0.07; p = 0.797]; NSSI frequency within the past 6 months was significantly reduced at T2 [ χ 2(1) = 12.45; p < 0.001] with no between-group difference [ χ 2(1) = 0.14; p = 0.704]. However, we found a significant group x point of measurement interaction [ χ 2(2) = 7.78; p = 0.021] regarding NSSI within the last month indicating at T1. CDP was equally effective and achieved faster recovery compared to a significantly more intensive TAU in treating adolescent NSSI. The CDP could provide a brief and pragmatic first treatment within a stepped-care model for NSSI in routine clinical care.

          Clinical Trial Registration The trial was prospectively registered in the German Registry of Clinical Trials ( https://www.drks.de; DRKS00003605) and is now complete.

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          The online version of this article (10.1007/s00787-019-01399-1) contains supplementary material, which is available to authorized users.

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          Most cited references18

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          Prevalence of nonsuicidal self-injury in nonclinical samples: systematic review, meta-analysis and meta-regression.

          Published prevalence estimates of nonsuicidal self-injury (NSSI) among nonclinical samples are highly heterogeneous, raising concerns about their reliability and hindering attempts to explore the alleged increase in NSSI over time. Accordingly, the objectives of this study were to investigate the influence of methodological factors on heterogeneity in NSSI prevalence estimates, explore changes over time, and estimate overall international NSSI prevalence. Results showed that methodological factors contributed over half (51.6%) of the heterogeneity in prevalence estimates, and, after adjusting for these factors, NSSI prevalence did not increase over time. Overall, pooled NSSI prevalence was 17.2% among adolescents, 13.4% among young adults, and 5.5% among adults. Clearly, development of standardized methodology in NSSI research is crucial if accurate estimates are desired. © 2014 The American Association of Suicidology.
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            Self-Injurious Thoughts and Behaviors Interview: development, reliability, and validity in an adolescent sample.

            The authors developed the Self-Injurious Thoughts and Behaviors Interview (SITBI) and evaluated its psychometric properties. The SITBI is a structured interview that assesses the presence, frequency, and characteristics of a wide range of self-injurious thoughts and behaviors, including suicidal ideation, suicide plans, suicide gestures, suicide attempts, and nonsuicidal self-injury (NSSI). This initial study, based on the administration of the SITBI to 94 adolescents and young adults, suggested that the SITBI has strong interrater reliability (average kappa = .99, r = 1.0) and test-retest reliability (average kappa = .70, intraclass correlation coefficient = .44) over a 6-month period. Moreover, concurrent validity was demonstrated via strong correspondence between the SITBI and other measures of suicidal ideation (average kappa = .54), suicide attempt (kappa = .65), and NSSI (average kappa = .87). The authors concluded that the SITBI uniformly and comprehensively assesses a wide range of self-injury-related constructs and provides a new instrument that can be administered with relative ease in both research and clinical settings. (PsycINFO Database Record (c) 2007 APA, all rights reserved).
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              Inter-rater reliability of the Structured Clinical Interview for DSM-IV Axis I Disorders (SCID I) and Axis II Disorders (SCID II).

              This study simultaneously assessed the inter-rater reliability of the Structured Clinical Interview for the Diagnostic and Statistical Manual of Mental Disorders Axis I (SCID I) and Axis II disorders (SCID II) in a mixed sample of n = 151 inpatients and outpatients, and non-patient controls. Audiotaped interviews were assessed by independent second raters blind for the first raters' scores and diagnoses. Categorical inter-rater reliability was assessed for 12 Axis I disorders of SCID I, while both categorical and dimensional inter-rater reliability was tested for all Axis II disorders. Results revealed moderate to excellent inter-rater agreement of the Axis I disorders, while most categorically and dimensionally measured personality disorders showed excellent inter-rater agreement. Copyright © 2010 John Wiley & Sons, Ltd.
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                Author and article information

                Contributors
                michael.kaess@upd.ch
                Journal
                Eur Child Adolesc Psychiatry
                Eur Child Adolesc Psychiatry
                European Child & Adolescent Psychiatry
                Springer Berlin Heidelberg (Berlin/Heidelberg )
                1018-8827
                1435-165X
                11 September 2019
                11 September 2019
                2020
                : 29
                : 6
                : 881-891
                Affiliations
                [1 ]GRID grid.5734.5, ISNI 0000 0001 0726 5157, University Hospital of Child and Adolescent Psychiatry and Psychotherapy, , University of Bern, ; Stöckli, Bolligenstrasse 141c, 3000 Bern 60, Switzerland
                [2 ]GRID grid.5253.1, ISNI 0000 0001 0328 4908, Section for Translational Psychobiology in Child and Adolescent Psychiatry, Clinic of Child and Adolescent Psychiatry, Centre for Psychosocial Medicine, , University Hospital Heidelberg, ; Heidelberg, Germany
                [3 ]GRID grid.5253.1, ISNI 0000 0001 0328 4908, Clinic of Child and Adolescent Psychiatry, Centre for Psychosocial Medicine, , University Hospital Heidelberg, ; Heidelberg, Germany
                [4 ]GRID grid.7727.5, ISNI 0000 0001 2190 5763, Clinic and Policlinic of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, , University of Regensburg, Regensburg District Hospital, ; Regensburg, Germany
                Author information
                http://orcid.org/0000-0002-1937-1085
                Article
                1399
                10.1007/s00787-019-01399-1
                7305262
                31512050
                1b0b149e-0d78-47ee-8541-0a78d58766d7
                © The Author(s) 2019

                Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License ( http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

                History
                : 15 April 2019
                : 30 August 2019
                Funding
                Funded by: FundRef http://dx.doi.org/10.13039/501100005941, Dietmar Hopp Stiftung;
                Award ID: 23011188
                Award Recipient :
                Categories
                Original Contribution
                Custom metadata
                © Springer-Verlag GmbH Germany, part of Springer Nature 2020

                Clinical Psychology & Psychiatry
                nonsuicidal self-injury,randomised controlled trial,adolescents,psychotherapy

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