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      Home Use of an Artificial Beta Cell in Type 1 Diabetes

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          Abstract

          The feasibility, safety, and efficacy of prolonged use of an artificial beta cell (closed-loop insulin-delivery system) in the home setting have not been established.

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          Outpatient glycemic control with a bionic pancreas in type 1 diabetes.

          Steven Russell, Firas H El-Khatib, Manasi Sinha … (2014)
          The safety and effectiveness of automated glycemic management have not been tested in multiday studies under unrestricted outpatient conditions.
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            Glycaemic control of Type 1 diabetes in clinical practice early in the 21st century: an international comparison.

            J. A. McKnight, S. H. Wild, M. J. E. Lamb … (2015)
            Improving glycaemic control in people with Type 1 diabetes is known to reduce complications. Our aim was to compare glycaemic control among people with Type 1 diabetes using data gathered in regional or national registries.
            Article 0 comments Cited 134 times – based on 0 reviews     Review now
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              Most Youth With Type 1 Diabetes in the T1D Exchange Clinic Registry Do Not Meet American Diabetes Association or International Society for Pediatric and Adolescent Diabetes Clinical Guidelines

              Jamie R. Wood, Kellee Miller, David Maahs … (2013)
              OBJECTIVE To assess the proportion of youth with type 1 diabetes under the care of pediatric endocrinologists in the United States meeting targets for HbA1c, blood pressure (BP), BMI, and lipids. RESEARCH DESIGN AND METHODS Data were evaluated for 13,316 participants in the T1D Exchange clinic registry younger than 20 years old with type 1 diabetes for ≥1 year. RESULTS American Diabetes Association HbA1c targets of <8.5% for those younger than 6 years, <8.0% for those 6 to younger than 13 years old, and <7.5% for those 13 to younger than 20 years old were met by 64, 43, and 21% of participants, respectively. The majority met targets for BP and lipids, and two-thirds met the BMI goal of <85th percentile. CONCLUSIONS Most children with type 1 diabetes have HbA1c values above target levels. Achieving American Diabetes Association goals remains a significant challenge for the majority of youth in the T1D Exchange registry.
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                Author and article information

                Journal
                Title: New England Journal of Medicine
                Abbreviated Title: N Engl J Med
                Publisher: Massachusetts Medical Society
                ISSN (Print): 0028-4793
                ISSN (Electronic): 1533-4406
                Publication date Created: November 26 2015
                Publication date (Print): November 26 2015
                Volume: 373
                Issue: 22
                Pages: 2129-2140
                Article
                DOI: 10.1056/NEJMoa1509351
                PubMed ID: 26379095
                SO-VID: 1b5d1623-4c4f-412a-a391-b67e450f8438
                Copyright © © 2015
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