11
views
0
recommends
+1 Recommend
1 collections
    0
    shares
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      ENANTIOSELECTIVE ADDITION OF DIETHYL ZINC TO BENZALDEHYDE CATALYZED BY TI(IV) AND GLUCOSE DERIVATIVES

      research-article

      Read this article at

      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          D-Glucose derivatives 1,2:5,6-di-O-isopropyline-a-D-glucofuranose (1) and 1,2-O-isopropyline-a-D-glucofuranose (2) with Ti(IV) are chiral catalysts in the addition of diethylzinc to benzaldehyde. The Ti(IV)-carbohydrate catalytic system is optimal with excess Ti(IV) and substoichiometric carbohydrate and 2 is the more active chiral catalyst probably because this derivative acts as a bidentate ligand in the proposed reaction. The arrangement of OH groups is crucial in determining the configuration of the alcohol product.

          Related collections

          Most cited references3

          • Record: found
          • Abstract: not found
          • Book: not found

          Asymmetric Catalysts in Organic Synthesis

            Bookmark
            • Record: found
            • Abstract: not found
            • Book: not found

            Comprehensive Asymmetric Catalysis

              Bookmark
              • Record: found
              • Abstract: not found
              • Book: not found

              Catalysis in Asymmetric Synthesis

                Bookmark

                Author and article information

                Journal
                jcchems
                Journal of the Chilean Chemical Society
                J. Chil. Chem. Soc.
                Sociedad Chilena de Química (Concepción, , Chile )
                0717-9707
                December 2010
                : 55
                : 4
                : 428-430
                Affiliations
                [01] orgnameUniversidad de Chile orgdiv1Facultad de Ciencias Químicas y Farmacéutica orgdiv2Departamento de Química Inorgánica Chile
                Article
                S0717-97072010000400003 S0717-9707(10)05500403
                10.4067/S0717-97072010000400003
                1b676f1a-7389-43bc-b55a-f5e614fd343e

                This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

                History
                : 26 November 2009
                : 07 July 2010
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 20, Pages: 3
                Product

                SciELO Chile


                Ti (IV)-carbohydrate,1- phenyl-1-propanol,glucose derivatives,diethylzinc

                Comments

                Comment on this article