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      Long Non-coding RNA MALAT1 Inhibits Neuron Apoptosis and Neuroinflammation While Stimulates Neurite Outgrowth and Its Correlation With MiR-125b Mediates PTGS2, CDK5 and FOXQ1 in Alzheimer's Disease.

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          Abstract

          This study aimed to investigate the effect of long noncoding ribonucleic acids (RNAs) metastasis-associated lung adenocarcinoma transcript 1 (lnc-MALAT1) on regulating neuron apoptosis, neurite outgrowth and inflammation, and further explore its molecule mechanism in Alzheimer's disease (AD).

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          Author and article information

          Journal
          Journal ID (iso-abbrev): Curr Alzheimer Res
          Title: Current Alzheimer research
          Publisher: Bentham Science Publishers Ltd.
          ISSN (Electronic): 1875-5828
          ISSN (Print): 1567-2050
          Publication date (Electronic): 2019
          Volume: 16
          Issue: 7
          Affiliations
          [1 ] Department of Pharmacy, Henan Provincial People's Hospital, Zhengzhou, China.
          [2 ] Department of Pharmacy, People's Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, China.
          [3 ] Department of Pharmacy, People's Hospital of Henan University, School of Clinical Medicine, Henan University, Zhengzhou, China.
          Article
          Publisher Item ID: CAR-EPUB-99969
          DOI: 10.2174/1567205016666190725130134
          PubMed ID: 31345147
          SO-VID: 1b838640-b893-4edd-87a7-0fe473f234eb
          History

          Keywords: Alzheimer's disease,Neuroinflammation,Neuron apoptosis,miR-125b,neurite outgrowth.,Lnc-MALAT1
          Data availability:
          Keywords: Alzheimer's disease, Neuroinflammation, Neuron apoptosis, miR-125b, neurite outgrowth., Lnc-MALAT1

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