Diffuse alveolar hemorrhage in coumarin users: a fibrosing interstitial pneumonia trigger?

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Abstract

Fibrosing interstitial pneumonias (IPs) include idiopathic pulmonary fibrosis (IPF) and nonspecific interstitial pneumonia (NSIP). It has been suggested that oxidative damage plays a role in the pathophysiology of idiopathic interstitial pneumonias. Diffuse alveolar hemorrhage (DAH) can cause oxidative stress. Accordingly, we hypothesized that episodes of DAH might trigger fibrosing IP development.

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Journal

Journal ID (iso-abbrev): Lung

Title: Lung

Publisher: Springer Science and Business Media LLC

ISSN (Electronic): 1432-1750

ISSN (Print): 0341-2040

Publication date (Electronic): Feb 2013

Volume: 191

Issue: 1

Affiliations

[1 ] Department of Clinical Chemistry, Maastricht University Medical Centre+ (MUMC+), Maastricht, The Netherlands.

Article

DOI: 10.1007/s00408-012-9436-2

PubMed ID: 23149804

SO-VID: 1bad8322-94b7-4aab-8e6a-33cf71ac3bcf

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