+1 Recommend
0 collections
      • Record: found
      • Abstract: found
      • Article: found
      Is Open Access

      Spontaneous Iliac Vein Ruptures: A Systematic Review


      Read this article at

          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.



          Spontaneous iliac vein rupture is a rare, but frequently lethal condition. It is important to timely recognize its clinical features and immediately start adequate treatment. We aimed to increase awareness to clinical features, specific diagnostics, and treatment strategies of spontaneous iliac vein rupture by evaluating the current literature.


          A systematic search was conducted in EMBASE, Ovid MEDLINE, Cochrane, Web of Science, and Google Scholar from inception until January 23, 2023, without any restrictions. Two reviewers independently screened for eligibility and selected studies describing a spontaneous iliac vein rupture. Patient characteristics, clinical features, diagnostics, treatment strategies, and survival outcomes were collected from included studies.


          We included 76 cases (64 studies) from the literature, mostly presenting with left-sided spontaneous iliac vein rupture (96.1%). Patients were predominantly female (84.2%), had a mean age of 61 years, and frequently presented with a concomitant deep vein thrombosis (DVT) (84.2%). After various follow-up times, 77.6% of the patients survived, either after conservative, endovascular, or open treatment. Endovenous or hybrid procedures were frequently performed if the diagnose was made before treatment, and almost all survived. Open treatment was common if the venous rupture was missed, for some cases leading to death.


          Spontaneous iliac vein rupture is rare and easily missed. The diagnose should at least be considered for middle-aged and elderly females presenting with hemorrhagic shock and concomitant left-sided DVT. There are various treatment strategies for spontaneous iliac vein rupture. An early diagnose brings options for endovenous treatment, which seems to have good survival outcomes based on previously described cases.

          Related collections

          Most cited references67

          • Record: found
          • Abstract: found
          • Article: found
          Is Open Access

          PRISMA 2020 explanation and elaboration: updated guidance and exemplars for reporting systematic reviews

          The methods and results of systematic reviews should be reported in sufficient detail to allow users to assess the trustworthiness and applicability of the review findings. The Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) statement was developed to facilitate transparent and complete reporting of systematic reviews and has been updated (to PRISMA 2020) to reflect recent advances in systematic review methodology and terminology. Here, we present the explanation and elaboration paper for PRISMA 2020, where we explain why reporting of each item is recommended, present bullet points that detail the reporting recommendations, and present examples from published reviews. We hope that changes to the content and structure of PRISMA 2020 will facilitate uptake of the guideline and lead to more transparent, complete, and accurate reporting of systematic reviews.
            • Record: found
            • Abstract: found
            • Article: not found

            CARE 2013 Explanations and Elaborations: Reporting Guidelines for Case Reports.

            Well-written and transparent case reports (1) reveal early signals of potential benefits, harms, and information on the use of resources; (2) provide information for clinical research and clinical practice guidelines (CPGs), and (3) inform medical education. High-quality case reports are more likely when authors follow reporting guidelines. During 2011-2012 a group of clinicians, researchers, and journal editors developed recommendations for the accurate reporting of information in case reports that resulted in the CARE (CAse REport) Statement and Checklist. They were presented at the 2013 International Congress on Peer Review and Biomedical Publication, have been endorsed by multiple medical journals, and translated into nine languages. This explanation and elaboration document has the objective to increase the use and dissemination of the CARE Checklist in writing and publishing case reports. Each item from the CARE Checklist is explained and accompanied by published examples. The explanations and examples in this document are designed to support the writing of high-quality case reports by authors and their critical appraisal by editors, peer reviewers, and readers. This article and the 2013 CARE Statement and Checklist, available from the CARE website [www.care-statement.org] and the EQUATOR Network, [www.equator-network.org] are resources for improving the completeness and transparency of case reports.
              • Record: found
              • Abstract: not found
              • Article: not found

              Categorization of patients as having provoked or unprovoked venous thromboembolism: guidance from the SSC of ISTH.


                Author and article information

                Vasc Endovascular Surg
                Vasc Endovascular Surg
                Vascular and Endovascular Surgery
                SAGE Publications (Sage CA: Los Angeles, CA )
                13 March 2023
                August 2023
                : 57
                : 6
                : 617-625
                [1 ]Department of Vascular Surgery, Ringgold 273198, universityErasmus Medical Center Rotterdam; , Rotterdam, The Netherlands
                [2 ]Department of Anesthesiology, Ringgold 273198, universityErasmus Medical Center Rotterdam; , Rotterdam, The Netherlands
                [3 ]Department of Urology, Ringgold 273198, universityErasmus Medical Center Rotterdam; , Rotterdam, The Netherlands
                [4 ]Department of Radiology and Nuclear Medicine, Ringgold 273198, universityErasmus Medical Center Rotterdam; , Rotterdam, The Netherlands
                Author notes
                [*]Jay M. Bakas, MD, Department of Vascular Surgery Erasmus Medical Center Rotterdam, Rotterdam 3000 CA, The Netherlands. Email: j.bakas@ 123456erasmusmc.nl
                [ * ]

                These authors contributed equally: A.L. Kooiman and J.M. Bakas (co-first authorship)

                Author information
                © The Author(s) 2023

                This article is distributed under the terms of the Creative Commons Attribution 4.0 License ( https://creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page ( https://us.sagepub.com/en-us/nam/open-access-at-sage).

                Review Articles
                Custom metadata

                rupture,spontaneous,iliac vein,venous,thrombosis,may-thurner syndrome,hematoma,case reports


                Comment on this article