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      Serum concentration of potassium in chronic heart failure patients administered spironolactone plus furosemide and either enalapril maleate, losartan potassium or candesartan cilexetil.

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          Abstract

          To retrospectively investigate elevation of serum potassium when spironolactone (25 or 50 mg/day) and furosemide were administered concomitantly with an angiotensin II converting enzyme inhibitor (ACE-I) or angiotensin II receptor blocker (ARB) to patients with chronic heart failure for 12 months and occurrence of hyperkalemia and hypokalemia because of concomitant administration of spironolactone plus an ACE-I or ARB and furosemide.

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          Author and article information

          Journal
          J Clin Pharm Ther
          Journal of clinical pharmacy and therapeutics
          Wiley
          0269-4727
          0269-4727
          Dec 2005
          : 30
          : 6
          Affiliations
          [1 ] Department of Pharmacy, National Hospital Organization Osaka Medical Center, Japan. m-saito@onh.go.jp
          Article
          JCP694
          10.1111/j.1365-2710.2005.00694.x
          16336294
          1bba6773-76bc-409c-b6ca-f060f6f83269
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