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      Extrusion and nixtamalization conditions influence the magnitude of change in the nutrients and bioactive components of cereals and legumes

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          Abstract

          Cereal and legume diets make up the bulk of caloric sources for a majority of households in the developing world. They contain macro‐ and micronutrients as well as phytochemicals embedded as one matrix. Some phytochemicals are antinutritional factors which can bind nutrients thereby hindering their bioavailability. While there are other methods that can be used to enhance nutrient utilization from such foods, we summarize how food processing methods such as extrusion and nixtamalization are employed to break the food matrix and release these nutrients. Both extrusion and nixtamalization can break down complex carbohydrates into simpler, more soluble forms while at the same time inactivating or denaturing protein inhibitors and other antinutritional factors. Such disruptions of complexes within the food matrix are essential for harnessing optimum nutritional and health benefit from these foods. We present mechanistic approaches explaining how these processes enhance nutrient and mineral bioavailability and phytochemical bioactivity while minimizing the undesirable effects of antinutritional factors that coexist in the complex food matrix.

          Abstract

          Extrusion and nixtamalization are employed to break the food matrix and release nutrients. Both processes break down complex carbohydrates into simpler, more soluble forms while at the same time inactivating or destroying protein inhibitors and other antinutritional factors. Disruptions of complexes within the food matrix are essential for harnessing optimum nutritional and health benefit from these foods.

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          Most cited references84

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          Role of advanced glycation end products in cellular signaling☆

          Improvements in health care and lifestyle have led to an elevated lifespan and increased focus on age-associated diseases, such as neurodegeneration, cardiovascular disease, frailty and arteriosclerosis. In all these chronic diseases protein, lipid or nucleic acid modifications are involved, including cross-linked and non-degradable aggregates, such as advanced glycation end products (AGEs). Formation of endogenous or uptake of dietary AGEs can lead to further protein modifications and activation of several inflammatory signaling pathways. This review will give an overview of the most prominent AGE-mediated signaling cascades, AGE receptor interactions, prevention of AGE formation and the impact of AGEs during pathophysiological processes.
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            Fermentation and germination improve nutritional value of cereals and legumes through activation of endogenous enzymes

            Abstract Cereals and legumes are outstanding sources of macronutrients, micronutrients, phytochemicals, as well as antinutritional factors. These components present a complex system enabling interactions with different components within food matrices. The interactions result in insoluble complexes with reduced bioaccessibility of nutrients through binding and entrapment thereby limiting their release from food matrices. The interactions of nutrients with antinutritional factors are the main factor hindering nutrients release. Trypsin inhibitors and phytates inherent in cereals and legumes reduce protein digestibility and mineral release, respectively. Interaction of phytates and phenolic compounds with minerals is significant in cereals and legumes. Fermentation and germination are commonly used to disrupt these interactions and make nutrients and phytochemicals free and accessible to digestive enzymes. This paper presents a review on traditional fermentation and germination processes as a means to address myriad interactions through activation of endogenous enzymes such as α‐amylase, pullulanase, phytase, and other glucosidases. These enzymes degrade antinutritional factors and break down complex macronutrients to their simple and more digestible forms.
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              Mechanisms underlying the cholesterol-lowering properties of soluble dietary fibre polysaccharides.

              A number of studies have shown a positive relationship between diets rich in soluble dietary fibres (SDF) such as β-glucan, pectin, guar gum and psyllium, and reduced serum cholesterol and thus a decreased risk of cardiovascular disease (CVD). Three major biological mechanisms have been proposed to explain the cholesterol-reducing effects of SDF: prevention of bile salt (BS) re-absorption from the small intestine leading to an excess faecal BS excretion; reduced glycemic response leading to lower insulin stimulation of hepatic cholesterol synthesis; and physiological effects of fermentation products of SDF, mainly propionate. Evidence for the latter mechanism is inconclusive, whereas in vivo, ex vivo and in vitro experiments suggest that BS micelles "bind" to SDF preventing their re-absorption. Whereas, glycemic responses to SDF have been studied extensively, the nature of interactions between bile salt micelles and SDF that lead to incomplete BS re-absorption are poorly defined. Three potential physicochemical mechanisms are proposed together with suggestions for in vitro experiments to test them.
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                Author and article information

                Contributors
                ekellyne@gmail.com
                Journal
                Food Sci Nutr
                Food Sci Nutr
                10.1002/(ISSN)2048-7177
                FSN3
                Food Science & Nutrition
                John Wiley and Sons Inc. (Hoboken )
                2048-7177
                25 February 2020
                April 2020
                : 8
                : 4 ( doiID: 10.1002/fsn3.v8.4 )
                : 1753-1765
                Affiliations
                [ 1 ] Department of Food Science and Nutrition University of Eldoret Eldoret Kenya
                [ 2 ] Department of Food Science and Nutrition Jomo Kenyatta University of Agriculture & Technology Nairobi Kenya
                [ 3 ] Department of Agro‐food Processing Natural Resources College Lilongwe University of Agriculture and Natural Resources Lilongwe Malawi
                Author notes
                [*] [* ] Correspondence

                Elijah Heka Kamau, Department of Food Science and Nutrition, University of Eldoret, Eldoret, Kenya.

                Email: ekellyne@ 123456gmail.com

                Author information
                https://orcid.org/0000-0001-6357-2581
                https://orcid.org/0000-0002-1936-9882
                Article
                FSN31473
                10.1002/fsn3.1473
                7174222
                32328241
                1bf52ade-ec73-45b8-8ae0-d32ea06108c5
                © 2020 The Authors. Food Science & Nutrition published by Wiley Periodicals, Inc.

                This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

                History
                : 13 September 2019
                : 20 December 2019
                : 10 January 2020
                Page count
                Figures: 4, Tables: 1, Pages: 13, Words: 11130
                Categories
                Review
                Reviews
                Custom metadata
                2.0
                April 2020
                Converter:WILEY_ML3GV2_TO_JATSPMC version:5.8.1 mode:remove_FC converted:21.04.2020

                antinutritional factor,extrusion,nixtamalization,nutrients,phytochemicals

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