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      Silver nanoparticles: synthesis through chemical methods in solution and biomedical applications

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      Open Chemistry
      Walter de Gruyter GmbH

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          Abstract

          Chemical methods provide an easy way to synthesize silver nanoparticles (Ag NPs) in solution. These metal nanoparticles have a great potential for biomedical applications as an antibacterial, antifungal, and antiviral agent or in wound healing. The adjustment of the parameters involved in these reactions permits a precise control over the size, shape, monodispersity, and the surfaces of the nanoparticles. These nanoparticles are being used in the design of new hybrid organic-inorganic or inorganic nanomaterials for biomedical applications.

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          Chemistry and properties of nanocrystals of different shapes.

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            Does the antibacterial activity of silver nanoparticles depend on the shape of the nanoparticle? A study of the Gram-negative bacterium Escherichia coli.

            In this work we investigated the antibacterial properties of differently shaped silver nanoparticles against the gram-negative bacterium Escherichia coli, both in liquid systems and on agar plates. Energy-filtering transmission electron microscopy images revealed considerable changes in the cell membranes upon treatment, resulting in cell death. Truncated triangular silver nanoplates with a {111} lattice plane as the basal plane displayed the strongest biocidal action, compared with spherical and rod-shaped nanoparticles and with Ag(+) (in the form of AgNO(3)). It is proposed that nanoscale size and the presence of a {111} plane combine to promote this biocidal property. To our knowledge, this is the first comparative study on the bactericidal properties of silver nanoparticles of different shapes, and our results demonstrate that silver nanoparticles undergo a shape-dependent interaction with the gram-negative organism E. coli.
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              Adsorption and surface-enhanced Raman of dyes on silver and gold sols

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                Author and article information

                Journal
                Open Chemistry
                Walter de Gruyter GmbH
                2391-5420
                January 1 2011
                January 1 2011
                : 9
                : 1
                Article
                10.2478/s11532-010-0124-x
                1c4fd699-aae0-4e07-b08b-df401dba3591
                © 2011
                History

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