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      Assessment of Echographic Regression Criteria in Ruthenium-Irradiated Melanoma

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          Abstract

          Steady flattening of the tumor, increasing reflectivity and decreasing vascularity are echographic signs of successful irradiation treatment. The specific example of an irradiated choroidal melanoma shows that the absence of echographic changes by no means excludes tumor destruction. Because of a dense vitreous body hemorrhage, the melanoma could only be evaluated echographically. Since the echogram lacked evidence of regression, the tumor was locally resected 5 months later. Histology, however, revealed an amorphous mass of dead tissue pervaded by intact vessels. Apparently a successfully irradiated melanoma may generate an echo typical of vital melanoma tissue. The authors therefore draw the conclusion that only a steady tumor growth, as substantiated by an echogram, may be considered an unambiguous sign of tumor vitality.

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          Author and article information

          Journal
          OPH
          Ophthalmologica
          10.1159/issn.0030-3755
          Ophthalmologica
          S. Karger AG
          0030-3755
          1423-0267
          1989
          1989
          31 March 2010
          : 198
          : 3
          : 129-134
          Affiliations
          aFirst University Eye Clinic (Head: Prof. H. Freyler) and bUniversity Clinic of Radiology and Radiobiology (Head: Prof. K. H. Kärcher), Vienna, Austria
          Article
          309975 Ophthalmologica 1989;198:129–134
          10.1159/000309975
          2657536
          © 1989 S. Karger AG, Basel

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          Page count
          Pages: 6
          Categories
          Original Paper

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