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      Potenciales provocados auditivos en niños con riesgo neonatal de hipoacusia Translated title: Auditory evoked potentials in children at neonatal risk for hypoacusis

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          Abstract

          Los potenciales provocados auditivos del tallo cerebral (PPATC) son un método sencillo y no invasor de evaluación de la función auditiva, que se utiliza ampliamente en niños para detectar tempranamente hipoacusia. Entre abril de 1992 y mayo de 1994, se estudiaron 400 niños mexicanos que presentaban, al menos, un factor de riesgo neonatal de hipoacusia. La media de la edad de los niños estudiados fue 6,6 meses y la media de la edad gestacional al nacer, 35,1 semanas. El 51% de ellos fueron tratados con amikacina. Se registraron 1 427 factores de riesgo (3,5 por niño), entre los que predominaron la exposición a ototóxicos, la hiperbilirrubinemia y el peso al nacer menor de 1 500 g. En 27% se encontraron alteraciones auditivas de tipo periférico y en 13%, ausencia de respuesta a estímulos auditivos. El bajo peso y la menor edad gestacional al nacer, la concentración máxima de bilirrubina en el suero, la presencia de sepsis, la hemorragia subependimaria o intraventricular, la ventilación mecánica y la exposición a ototóxicos se asociaron significativamente con la presencia de hipoacusia grave o profunda.

          Translated abstract

          Auditory evoked potentials of the brain stem (AEPBS) provide a simple, noninvasive method of evaluating hearing function and have been widely used for early detection of hypoacusis in children. Between April 1992 and May 1994, a study was done of 400 Mexican children who presented at least one neonatal risk factor for hearing impairment. The average age of the children studied was 6.6 months and their average gestational age at birth was 35.1 weeks. Just over half of them (51%) had been treated with amikacin. The study found 1 427 risk factors (3.5 per child), the most common ones being exposure to ototoxic substances, hyperbilirubinemia, and birthweight of less that 1 500 g. In 27% of the children, peripheral auditory changes were found, and 13% did not respond to auditory stimuli. Low birthweight and young gestational age at birth, high serum concentration of bilirubin, sepsis, subependymal or intraventricular hemorrhage, mechanical ventilation, and exposure to ototoxic substances were significantly associated with the presence of severe or profound hypoacusis.

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          AUDITORY-EVOKED FAR FIELDS AVERAGED FROM THE SCALP OF HUMANS

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            Diseases of the nervous system in childhood

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              Auditory nerve and brainstem responses in newborn infants with hyperbilirubinemia.

              To assess early bilirubin toxicity, a study was made of auditory brainstem responses in relation to total bilirubin levels as well as unbound bilirubin levels in 56 hyperbilirubinemic infants (total bilirubin greater than or equal to 15.0 mg/dL) and 24 infants who did not have jaundice. The latencies of wave I at 85 dB HL (hearing level) in hyperbilirubinemic infants were significantly greater than those in the control group. The latencies of wave I and V in hyperbilirubinemic infants with unbound bilirubin levels greater than or equal to 1.0 microgram/dL (group C) were greater than those in the control group and in the hyperbilirubinemic infants with unbound bilirubin levels less than 0.5 microgram/dL (group A) and with unbound bilirubin levels less than 1.0 microgram/dL (group B). There were no significant differences of the wave I-V interpeak latency between the control infants and the hyperbilirubinemic infants. Thirty of the 80 infants showed prolonged peak latencies (greater than the mean +/- 2 SD for the control infants) of wave I and/or V in one or both ears. The incidences of the prolonged peak latencies in group B (42%) and group C (89%) were significantly greater than that in the control group (12%). The serial determinations of auditory brainstem responses in infants treated with exchange transfusions revealed that the prolonged peak latencies before exchange transfusion improved at 48 and 96 hours after the procedure for wave I, and at 24, 48, and 96 hours after the procedure for wave V. The interpeak latency of wave I-V did not change with exchange transfusion.(ABSTRACT TRUNCATED AT 250 WORDS)
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                Author and article information

                Journal
                rpsp
                Revista Panamericana de Salud Pública
                Rev Panam Salud Publica
                Organización Panamericana de la Salud (Washington, Washington, United States )
                1020-4989
                1680-5348
                February 1997
                : 1
                : 2
                : 119-124
                Affiliations
                [03] México DF orgnameSecretaría de Salud orgdiv1 Instituto Nacional de Perinatología, Departamento de Seguimiento Pediátrico México
                [01] México DF orgnameSecretaría de Salud orgdiv1 Instituto Nacional de Perinatología, Departamento de Neurología Perinatal México
                [02] México DF orgnameInstituto de Seguridad y Servicios Sociales para los Trabajadores del Estado orgdiv1 Centro Médico "20 de noviembre", Departamento de Enseñanza México
                Article
                S1020-49891997000200005 S1020-4989(97)00100205
                10.1590/s1020-49891997000200005
                1c58c6dc-35ae-416d-843a-becaee8bb6db

                This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

                History
                : 25 October 1995
                : 06 May 1996
                Page count
                Figures: 0, Tables: 0, Equations: 0, References: 23, Pages: 6
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                SciELO Public Health

                Self URI: Texto completo solamente en formato PDF (ES)
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