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      EFFECT OF WAR AND POSTWAR GENOTOXINS ON MICRONUCLEI FREQUENCY IN SARAJEVO STUDY GROUP

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          Abstract

          During the 1992 – 1995 siege, as well as after the war activities, citizens of Sarajevo were most probably exposed to various potential genotoxic agents. The effects of those potential genotoxins were evaluated by micronucleus – cytokinesis blocked assay. The study included 30 individuals who resided in the area of Sarajevo during the war and the postwar period. Point biserial coefficient analysis did not reveal any relationship between the frequencies of binuclear cells with micronuclei as well as total number of micronuclei and smoking habits or gender. Simple linear regression revealed statistically significant positive correlation between the age and micronuclei formation. Due to the war related environmental contamination more extensive study is recommended.

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          Author and article information

          Journal
          Bosn J Basic Med Sci
          Bosn J Basic Med Sci
          BJBMS
          Bosnian Journal of Basic Medical Sciences
          Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina (Bosnia )
          1512-8601
          1840-4812
          November 2006
          : 6
          : 4
          : 54-57
          Affiliations
          [1 ]Institute for Genetic Engineering and Biotechnology, University of Sarajevo, Kemalbegova 10, 71000 Sarajevo, Bosnia and Herzegovina
          [2 ]Faculty of Medicine, University of Sarajevo, Čekaluša 90, 71 000 Sarajevo, Bosnia and Herzegovina
          Author notes
          [* ]Corresponding author
          Article
          PMC5807971 PMC5807971 5807971 BJBMS-6-54
          5807971
          17177651
          1c81781c-d7b8-44c0-a0cd-b75f35f2e99e
          Copyright: © 2006 ABMSFBIH
          History
          Categories
          Article

          war related genotoxins,binuclear lymphocytes,micro nuclei

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