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      Osmotic Pressure Variations in the Aqueous Humour and their Influence on Outflow Facility

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          Abstract

          A report is given of an experimental study on enucleated rabbit eyes concerning the influence of intraocular pressure and osmotic pressure of the aqueous humour on outflow facility. The outflow facility has been shown to be influenced by the perfusion time and the aqueous composition. When crystalloid-osmotic or colloid-osmotic pressure of the aqueous were elevated by-means of glucose or Ficoll®, a significant decrease in outflow facility resulted. This might be caused by the rise in viscosity (Ficoll) or/and by the obstruction of the filtering membranes (glucose).

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          Author and article information

          Journal
          ORE
          Ophthalmic Res
          10.1159/issn.0030-3747
          Ophthalmic Research
          S. Karger AG
          0030-3747
          1423-0259
          1976
          1976
          03 December 2009
          : 8
          : 1
          : 7-16
          Affiliations
          Clinical Institute for Experimental Ophthalmology, University of Bonn (Director: Prof. E. Weigelin), Bonn
          Article
          264794 Ophthalmic Res 1976;8:7–16
          10.1159/000264794
          1cbe6a75-072e-443b-9099-e01256853323
          © 1976 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          History
          : 28 June 1974
          : 07 January 1975
          Page count
          Pages: 10
          Categories
          Paper

          Vision sciences,Ophthalmology & Optometry,Pathology
          Aqueous humour,Intraocular pressure,Per-fusion time,Rabbit,Osmolality,Outflow facility

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