Gap junction connexins in female reproductive organs: implications for women&apos;s reproductive health.

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Abstract

Connexins comprise a family of ~20 proteins that form intercellular membrane channels (gap junction channels) providing a direct route for metabolites and signalling molecules to pass between cells. This review provides a critical analysis of the evidence for essential roles of individual connexins in female reproductive function, highlighting implications for women's reproductive health.

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Author and article information

Journal

Journal ID (iso-abbrev): Hum Reprod Update

Title: Human reproduction update

Publisher: Oxford University Press (OUP)

ISSN (Electronic): 1460-2369

ISSN (Print): 1355-4786

Publication date (Electronic): February 11 2015

Volume: 21

Issue: 3

Affiliations

[1 ] Institute of Molecular Biology, University of Duisburg-Essen, University Clinics, 45211 Essen, Germany elke.winterhager@uk-essen.de.

[2 ] Department of Physiology and Pharmacology, Schulich School of Medicine and Dentistry, The University of Western Ontario and Children's Health Research Institute, London, Ontario N6C 2V5, Canada.

Article

Publisher Item ID: dmv007

DOI: 10.1093/humupd/dmv007

PubMed ID: 25667189

SO-VID: 1cdc455e-b427-495a-8243-d9790b1a4ee2

Copyright © © The Author 2015. Published by Oxford University Press on behalf of the European Society of Human Reproduction and Embryology. All rights reserved. For Permissions, please email: journals.permissions@oup.com.