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      Interventions to improve the quality of bystander cardiopulmonary resuscitation: A systematic review

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          Abstract

          Background

          Performing high-quality bystander cardiopulmonary resuscitation (CPR) improves the clinical outcomes of victims with sudden cardiac arrest. Thus far, no systematic review has been performed to identify interventions associated with improved bystander CPR quality.

          Methods

          We searched Ovid MEDLINE, Ovid EMBASE, EBSCO CINAHL, Ovid PsycInfo, Thomson Reuters SCI-EXPANDED, and the Cochrane Central Register of Controlled Trials to retrieve studies published from 1 January 1966 to 5 October 2018 associated with interventions that could improve the quality of bystander CPR. Data regarding participant characteristics, interventions, and design and outcomes of included studies were extracted.

          Results

          Of the initially identified 2,703 studies, 42 were included. Of these, 32 were randomized controlled trials. Participants included adults, high school students, and university students with non-medical professional majors. Interventions improving bystander CPR quality included telephone dispatcher-assisted CPR (DA-CPR) with simplified or more concrete instructions, compression-only CPR, and other on-scene interventions, such as four-hand CPR for elderly rescuers, kneel on opposite sides for two-person CPR, and CPR with heels for a tired rescuer. Devices providing real-time feedback and mobile devices containing CPR applications or software were also found to be beneficial in improving the quality of bystander CPR. However, using mobile devices for improving CPR quality or for assisting DA-CPR might cause rescuers to delay starting CPR.

          Conclusions

          To further improve the clinical outcomes of victims with cardiac arrest, these effective interventions may be included in the guidelines for bystander CPR.

          Related collections

          Most cited references48

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          Quality of out-of-hospital cardiopulmonary resuscitation with real time automated feedback: a prospective interventional study.

          To compare quality of CPR during out-of-hospital cardiac arrest with and without automated feedback. Consecutive adult, out-of-hospital cardiac arrests of all causes were studied. One hundred and seventy-six episodes (March 2002-October 2003) without feedback were compared to 108 episodes (October 2003-September 2004) where automatic feedback on CPR was given. Automated verbal and visual feedback was based on measured quality with a prototype defibrillator. Quality of CPR was the main outcome measure and survival was reported as specified in the protocol. Average compression depth increased from (mean +/- S.D.) 34 +/- 9 to 38 +/- 6 mm (mean difference (95% CI) 4 (2, 6), P < 0.001), and median percentage of compressions with adequate depth (38-51 mm) increased from 24% to 53% (P < 0.001, Mann-Whitney U-test) with feedback. Mean compression rate decreased from 121 +/- 18 to 109 +/- 12 min(-1) (difference -12 (-16, -9), P = 0.001). There were no changes in the mean number of ventilations per minute; 11 +/- 5 min(-1) versus 11 +/- 4 min(-1) (difference 0 (-1, 1), P = 0.8) or the fraction of time without chest compressions; 0.48 +/- 0.18 versus 0.45 +/- 0.17 (difference -0.03 (-0.08, 0.01), P = 0.08). With intention to treat analysis 7/241 control patients were discharged alive (2.9%) versus 5/117 with feedback (4.3%) (OR 1.5 (95% CI; 0.8, 3), P = 0.2). In a logistic regression analysis of all cases, witnessed arrest (OR 4.2 (95% CI; 1.6, 11), P = 0.004) and average compression depth (per mm increase) (OR 1.05 (95% CI; 1.01, 1.09), P = 0.02) were associated with rate of hospital admission. Automatic feedback improved CPR quality in this prospective non-randomised study of out-of-hospital cardiac arrest. Increased compression depth was associated with increased short-term survival. ClinicalTrials.gov (NCT00138996), http://www.clinicaltrials.gov/.
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            • Article: not found

            What is the optimal chest compression depth during out-of-hospital cardiac arrest resuscitation of adult patients?

            The 2010 American Heart Association guidelines suggested an increase in cardiopulmonary resuscitation compression depth with a target >50 mm and no upper limit. This target is based on limited evidence, and we sought to determine the optimal compression depth range.
              • Record: found
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              Part 3: Adult basic life support and automated external defibrillation: 2015 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science with Treatment Recommendations.

                Author and article information

                Contributors
                Role: ConceptualizationRole: Data curationRole: Formal analysisRole: InvestigationRole: MethodologyRole: SoftwareRole: Writing – original draft
                Role: InvestigationRole: Methodology
                Role: ConceptualizationRole: Data curationRole: Formal analysisRole: InvestigationRole: MethodologyRole: ResourcesRole: SoftwareRole: Writing – original draft
                Role: ConceptualizationRole: ResourcesRole: SoftwareRole: Writing – review & editing
                Role: ConceptualizationRole: Funding acquisitionRole: MethodologyRole: ResourcesRole: SoftwareRole: Writing – review & editing
                Role: Editor
                Journal
                PLoS One
                PLoS ONE
                plos
                plosone
                PLoS ONE
                Public Library of Science (San Francisco, CA USA )
                1932-6203
                13 February 2019
                2019
                : 14
                : 2
                : e0211792
                Affiliations
                [1 ] College of Medicine, National Taiwan University, Taipei, Taiwan
                [2 ] Department of Emergency Medicine, National Taiwan University Hospital, Taipei, Taiwan
                [3 ] Department of Emergency Medicine, National Taiwan University Hospital Yun-Lin Branch, Yun-Lin County, Taiwan
                St. Michael’s Hospital, CANADA
                Author notes

                Competing Interests: The authors have declared that no competing interests exist.

                ‡ These authors also contributed equally to this work.

                Author information
                http://orcid.org/0000-0002-4388-9984
                Article
                PONE-D-18-17615
                10.1371/journal.pone.0211792
                6373936
                30759140
                1d53ca69-c6a6-4c67-a726-532116283745
                © 2019 Chen et al

                This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

                History
                : 12 June 2018
                : 21 January 2019
                Page count
                Figures: 1, Tables: 5, Pages: 27
                Funding
                Funded by: funder-id http://dx.doi.org/10.13039/501100004663, Ministry of Science and Technology, Taiwan;
                Award ID: MOST 105-2314-B-002-026
                Award Recipient :
                Funded by: funder-id http://dx.doi.org/10.13039/501100004663, Ministry of Science and Technology, Taiwan;
                Award ID: MOST 106-2314-B-002-091
                Award Recipient :
                Funded by: funder-id http://dx.doi.org/10.13039/501100004663, Ministry of Science and Technology, Taiwan;
                Award ID: MOST 105-2314-B-002 -200 -MY3
                Award Recipient :
                Funded by: funder-id http://dx.doi.org/10.13039/501100005762, National Taiwan University Hospital;
                Award ID: 108-09
                Award Recipient :
                The article was supported by the Taiwan Ministry of Science and Technology (MOST 105-2314-B-002-026, MOST 105-2314-B-002 -200 -MY3, MOST 107-2314-B-002 -001 and MOST 106-2314-B-002-091) and National Taiwan University Hospital (108-09).
                Categories
                Research Article
                Medicine and Health Sciences
                Critical Care and Emergency Medicine
                Resuscitation
                Computer and Information Sciences
                Data Compression
                Engineering and Technology
                Equipment
                Communication Equipment
                Telephones
                Engineering and Technology
                Equipment
                Communication Equipment
                Cell Phones
                Computer and Information Sciences
                Computer Software
                Medicine and Health Sciences
                Cardiology
                Cardiac Arrest
                Biology and Life Sciences
                Anatomy
                Musculoskeletal System
                Body Limbs
                Arms
                Hands
                Medicine and Health Sciences
                Anatomy
                Musculoskeletal System
                Body Limbs
                Arms
                Hands
                Research and Analysis Methods
                Research Assessment
                Systematic Reviews
                Custom metadata
                All relevant data are within the paper and its Supporting Information files.

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