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      Depression Is Associated With High Levels of C-Reactive Protein and Low Levels of Fractional Exhaled Nitric Oxide: Results From the 2007-2012 National Health and Nutrition Examination Surveys.

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          Abstract

          Major depressive disorder may be due to psychoneuroimmunological dysfunction, as studies have documented increased levels of a variety of inflammatory mediators in depressed subjects. Nitric oxide (NO) is marker of inflammation, and fractional exhaled NO (FeNO) is a marker of airway inflammation. Plasma NO and FeNO levels have been shown to be lower in subjects with depression in small studies. We sought to assess the association of depression with C-reactive protein (CRP) and FeNO levels in a large and representative sample of the US population.

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          Author and article information

          Journal
          J Clin Psychiatry
          The Journal of clinical psychiatry
          Physicians Postgraduate Press, Inc
          1555-2101
          0160-6689
          Dec 2016
          : 77
          : 12
          Affiliations
          [1 ] Janssen Research & Development, LLC, 1125 Trenton Harbourton Rd, Titusville, NJ 08560. scepeda@its.jnj.com.
          [2 ] Department of Epidemiology, Janssen Research & Development, LLC, Titusville, New Jersey, USA.
          Article
          10.4088/JCP.15m10267
          27337107
          1da4513d-6a7f-46db-b371-9627910ab09e
          History

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