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Increased Prostate Cancer Glucose Metabolism Detected by 18 F-fluorodeoxyglucose Positron Emission Tomography/Computed Tomography in Localised Gleason 8–10 Prostate Cancers Identifies Very High–risk Patients for Early Recurrence and Resistance to Castration
Etienne Lavallée ,
Michelle Bergeron ,
François-Alexandre Buteau ,
Annie-Claude Blouin ,
Nicolas Duchesnay ,
Thierry Dujardin ,
Rabi Tiguert ,
Louis Lacombe ,
Vincent Fradet ,
Molière Makao-Nguile ,
Yves Fradet ,
Jean-Mathieu Beauregard ,
Frédéric Pouliot
March 2018
March 2018
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Abstract
The accuracy of 18F-fluorodeoxyglucose positron emission tomography/computed tomography
(FDG-PET/CT) to stage prostate cancer (PCa) is limited. However, Gleason 8-10 PCa
and more aggressive metastatic PCa have been shown to exhibit a higher glycolytic
activity.