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      The potential of photodynamic therapy (PDT)-Experimental investigations and clinical use.

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          Abstract

          Photodynamic therapy (PDT) is an intensively studied part of medicine based on free radicals. These reactive species, extremely harmful for whole human organism, are used for eradication numerous diseases. Specific structure of ill tissues causes accumulation free radicals inside them without attack remaining healthy tissues. A rapid development of medicine and scientific research has led to extension of PDT towards treatment many diseases such as cancer, herpes, acne and based on antimicrobials. The presented review article is focused on the aforementioned disorders with accurate analysis of the newest available scientific achievements. The discussed cases explicitly indicate on high efficacy of the therapy. In most cases, free radicals turned out to be solution of many afflictions. Photodynamic therapy can be considered as promising treatment with comparable effectiveness but without side effects characteristic for chemotherapy.

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          Author and article information

          Journal
          Biomed. Pharmacother.
          Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
          Elsevier BV
          1950-6007
          0753-3322
          Oct 2016
          : 83
          Affiliations
          [1 ] Department of Inorganic Chemistry, Medical University of Lublin, Chodzki 4a, 20-093 Lublin, Poland. Electronic address: anoniszczuk@o2.pl.
          [2 ] Department of Inorganic Chemistry, Medical University of Lublin, Chodzki 4a, 20-093 Lublin, Poland. Electronic address: k.wojtunik@o2.pl.
          [3 ] Department of Food Process Engineering, Lublin University of Life Sciences, 44 Doświadczalna Street, 20-236 Lublin, Poland. Electronic address: tomasz.oniszczuk@up.lublin.pl.
          [4 ] Department of Inorganic Chemistry, Medical University of Lublin, Chodzki 4a, 20-093 Lublin, Poland. Electronic address: kasprzak.kamila.k@o2.pl.
          Article
          S0753-3322(16)30559-5
          10.1016/j.biopha.2016.07.058
          27522005

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