A 48-year-old woman was unable to walk due to an extensive osteolytic supra-acetabular iliac wing metastatic lymphoma involving the arcuate line. A minimally invasive technique that combined percutaneous nailing of the iliac bone with a customized nail and cementoplasty (intraosseous injection of polymethylmethacrylate) was performed. At the 1-year follow-up, she was able to walk without crutches, and computed tomography (CT) showed a stable iliac bone fixation.