Influence of Left Ventricular Isovolumic Pressure Upon Right Ventricular Pressure Transients

Abstract

Simultaneous, high-fidelity pressure recordings were obtained from the left and right ventricles of anesthetized dogs. Abrupt elevation of left ventricular pressure produced an immediate rise in right ventricular systolic pressure, while mechanical asynchrony of the two ventricles, induced by endocardial pacing of either ventricle, identified discrete pressure transients in the right ventricular pressure pulse which occurred coincident with peak left ventricular dP/dt. During normal conduction, peak right ventricular dP/dt regularly occurred after pulmonic valve opening and simultaneously with peak left ventricular dP/dt. Thus, the rising portion of the right ventricular pressure pulse is an impure signal, influenced directly by the amplitude and timing of left ventricular isovolumic pressure. These observations suggest that right ventricular pumping function is aided by an in series left ventricle.

Journal

Journal ID (publisher-id): CRD

Journal ID (nlm-ta): Cardiology

Journal ID (doi): 10.1159/issn.0008-6312

Title: Cardiology

Publisher: S. Karger AG

ISSN (Print): 0008-6312

ISSN (Electronic): 1421-9751

Publication date Subscription-year: 1973

Publication date (Print): 1973

Publication date (Electronic): 29 October 2008

Volume: 58

Issue: 1

Pages: 32-44

Affiliations

New England Medical Center Hospitals and the Department of Medicine, Tufts University School of Medicine, Boston, Mass

Article

Publisher ID: 169617 Other ID: Cardiology 1973;58:32–44

DOI: 10.1159/000169617

PubMed ID: 4710798

Copyright statement: © 1973 S. Karger AG, Basel

License:

Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

Page count

Pages: 13

Product

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Self URI (text/html): https://www.karger.com/Article/FullText/169617

Self URI (journal page): https://www.karger.com/SubjectArea/Cardiovascular-System

Categories

Subject: Paper