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      Identification of 34 apolipoprotein(a) isoforms: differential expression of apolipoprotein(a) alleles between American blacks and whites.

      Biochemical and Biophysical Research Communications
      African Continental Ancestry Group, genetics, Alleles, Apolipoproteins, Apoprotein(a), Electrophoresis, Polyacrylamide Gel, European Continental Ancestry Group, Gene Frequency, Humans, Lipoprotein(a), United States

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          Abstract

          A total of 34 different apo(a) isoforms was identified in a population sample of 806 American Whites and 701 American Blacks by a high resolution SDS-agarose gel electrophoretic method followed by immunoblotting. Among the 1507 individuals tested, 79% revealed double-banded phenotypes and 21% single-banded phenotypes. The frequencies of the apo(a) isoforms differed between American Blacks and Whites (p < 0.001).

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