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The importance of taxon sampling in genomic studies: An example from the cyclooxygenases of teleost fishes
July 2010
July 2010
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Abstract
Comparative genomic studies must often rely on single model species and exemplars
to represent the genetic variation both within and among different major groups, because
of technological, financial, and time constraints. This study of the cyclooxygenases
from teleost fishes serves as a reminder that caution is required in these cases,
since such incomplete taxon sampling can lead to errors in the interpretation and
prediction of genome evolution, function, and structure.