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      Alpha-2 adrenergic receptor agonists: a review of current clinical applications.

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          Abstract

          The α-2 adrenergic receptor agonists have been used for decades to treat common medical conditions such as hypertension; attention-deficit/hyperactivity disorder; various pain and panic disorders; symptoms of opioid, benzodiazepine, and alcohol withdrawal; and cigarette craving. (1) However, in more recent years, these drugs have been used as adjuncts for sedation and to reduce anesthetic requirements. This review will provide an historical perspective of this drug class, an understanding of pharmacological mechanisms, and an insight into current applications in clinical anesthesiology.

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          Author and article information

          Journal
          Anesth Prog
          Anesthesia progress
          0003-3006
          0003-3006
          2015
          : 62
          : 1
          Affiliations
          [1 ] Professor and Chair and.
          Article
          10.2344/0003-3006-62.1.31
          25849473
          1fbc6a72-0748-464c-bcf5-17ecccb07975
          History

          Alpha-2 agonists,Clonidine,Dexmedetomidine,General anesthesia,Procedural sedation

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