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      Chemical Reactivity of Aluminium-based Pharmaceutical Compounds used as Phosphate-binders

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          Most cited references 11

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          Alzheimer's disease: X-ray spectrometric evidence of aluminum accumulation in neurofibrillary tangle-bearing neurons.

          The elemental content of neurons of the hippocampus was studied by a combination of scanning electron microscopy and x-ray spectrometry in autopsy-derived brain tissue from three cases of senile dementia (Alzheimer type) and three nondemented elderly controls. Foci of aluminum were detected within the nuclear region of a high percentage of neurons containing neurofibrillary tangles from the cases of senile dementia as well as the elderly controls. The adjacent normal-appearing neurons from both groups of patients were virtually free of detectable aluminum. These findings suggest that the association of aluminum to Alzheimer's disease extends to the neuronal level.
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            Gastrointestinal Absorption of Aluminum from Aluminum-Containing Antacids

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              Kinetics of the adsorption-desorption of phosphate on the .gamma.-alumina surface using the pressure-jump technique

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                Author and article information

                Journal
                Journal of Pharmacy and Pharmacology
                Wiley
                00223573
                January 1989
                January 1989
                April 12 2011
                : 41
                : 1
                : 11-16
                Article
                10.1111/j.2042-7158.1989.tb06320.x
                © 2011

                http://doi.wiley.com/10.1002/tdm_license_1.1

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