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      Effectiveness of penfluridol (oral long acting neuroleptic) as compared to second generation oral neuroleptics in psychotic disorder patients: an open label randomized controlled trial - ZonMw

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          Abstract

          Non-adherence with antipsychotics is common in patients with a psychotic disorder and is associated with more relapses and higher healtcare costs. Penfluridol is a first generation antipsychotic drug and currently the only long-acting oral agent that can be taken once a week. Second generation oral antipsychotic drugs such as olanzapine and risperidone have to be taken daily. In addition, penfluridol is also cheaper than oral second-generation antipsychotics mostly used today (including olanzapine and risperidone). Since this agent can be administered on a weekly basis, we expect that penfluridol will enhance patient adherence and therefore lower healthcare costs . This multi-center open label randomized controlled trial will provide an initial insight into the (cost-) effectiveness of this agent as compared to second generation antipsychotics, and whether the clinical guidelines could be updated.

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          Journal
          Impact
          impact
          Science Impact, Ltd.
          2398-7073
          August 08 2017
          August 08 2017
          : 2017
          : 6
          : 22-24
          Article
          10.21820/23987073.2017.6.22
          © 2017

          This work is licensed under a Creative Commons Attribution 4.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

          Earth & Environmental sciences, Medicine, Computer science, Agriculture, Engineering

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