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      Peptide antibiotics.

      1

      Lancet (London, England)

      Elsevier BV

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          Abstract

          The era of the "classical antibiotic" may be over. The emergence of resistance has seen to that. Yet no truly novel class of antibacterial agent has come on the market in the past 30 years. Currently there is great interest in peptide antibiotics, especially the cationic peptides. Thousands of such molecules have been synthesised and just a few are entering clinical trials. Because they kill bacteria quickly by the physical disruption of cell membranes, peptide antibiotics may not face the rapid emergence of resistance.

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          Author and article information

          Journal
          Lancet
          Lancet (London, England)
          Elsevier BV
          0140-6736
          0140-6736
          Feb 08 1997
          : 349
          : 9049
          Affiliations
          [1 ] Department of Microbiology and immunology, University of British Columbia, Vancouver, Canada.
          Article
          S0140-6736(97)80051-7
          10.1016/S0140-6736(97)80051-7
          9033483
          201e9a53-99a9-4d7a-a86a-200039ff8fff

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