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      Anti-beta(1)-adrenergic receptor antibodies and heart failure: causation, not just correlation.

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      Journal: The Journal of clinical investigation
      Publisher: American Society for Clinical Investigation

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          Abstract

          Antibodies specific for the beta(1)-adrenergic receptor are found in patients with chronic heart failure of various etiologies. From work presented in this issue of the JCI, we can now infer that these antibodies actually contribute to the pathogenesis of chronic heart failure. This commentary discusses mechanisms by which these antibodies may engender cardiomyopathy.

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          PubMed ID:: 15146232
          PMC ID:: 406535
          DOI:: 10.1172/JCI21748

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