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      Pulmonary Air Embolism: An Infrequent Complication in the Radiology Suite

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          Abstract

          Patient: Female, 64

          Final Diagnosis: Pulmonary air embolism

          Symptoms: Shortness of breath

          Medication: —

          Clinical Procedure: —

          Specialty: Critical Care Medicine

          Objective:

          Unusual or unexpected effect of treatment

          Background:

          Air embolism can occur in a number of medical-surgical situations. Venous air embolism is frequently lethal when a substantial amount enters the venous circulation rapidly and can lead to significant morbidity if crossover to the systemic arterial circulation occurs. The diagnosis of massive air embolism is usually made on clinical grounds by the development of abrupt hemodynamic compromise. The true incidence, morbidity, and mortality of this event is unknown given the difficulties in diagnosis.

          Case Report:

          An inadvertent antecubital venous injection of 150 mL of air using a contrast power injector during a computed tomography (CT) is reported. Immediate imaging (CT) showed a significant amount of air in the right atrium and right ventricular cavity, and air mixed with contrast in the main pulmonary artery and proximal divisions of the pulmonary circulation. Patient condition deteriorated requiring mechanical ventilation for 48 hours. Condition improved over the next few days and patient was successfully extubated and discharged home.

          Conclusions:

          Air embolism is a rare complication, the potential for this to be life threatening makes prevention and early detection of this condition essential. This condition should be suspected when patients experience sudden onset respiratory distress and/or experience a neurological event in the setting of a known risk factor. Treatment options include Durant’s maneuver; left-lateral decubitus, head-down positioning; to decrease air entry into the right ventricle outflow tract, hyperbaric therapy, 100% O 2 and supportive care.

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          Most cited references17

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          Venous air embolism: clinical and experimental considerations.

          S Orebaugh (1992)
          To examine the existing literature concerning venous air embolism. Causes, pathophysiology, and management are emphasized. The literature that was reviewed was retrieved from the MEDLINE System under the headings "venous air embolism," "air embolism," "therapy of air embolism," "etiology of venous air embolism," and "pathophysiology of venous air embolism" for the years 1970 to 1991. A manual search, derived from the references of these papers, was performed to obtain relevant citations for the years preceding 1970. Experimental (animal) data, case reports, case series, and clinical investigations are included. Venous air embolism is an infrequent complication of invasive diagnostic and therapeutic maneuvers. The cardiovascular, pulmonary, and central nervous systems may all be affected, with severity ranging from no symptoms to immediate cardiovascular collapse. Therapeutic interventions include mechanical measures, such as positioning, withdrawal of air from the right atrium, and measures aimed at reducing bubble size. Hyperbaric oxygen therapy holds some promise in accomplishing the latter, but randomized, controlled trials demonstrating efficacy have yet to be performed.
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            • Record: found
            • Abstract: not found
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            Volume of air in a lethal venous air embolism.

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              Nonfatal venous air embolism after contrast-enhanced CT.

              Contrast material-enhanced computed tomography (CT) was performed in 100 patients. Fifty milliliters of contrast material was intravenously injected by hand and followed by a drip infusion of 100 mL of contrast material. Venous air embolism occurred in 23% of the patients. The amount of embolism was minimal in 20 patients and moderate in three. Although large amounts of embolism have been reported to be associated with considerable morbidity and mortality, none of the patients in this study had immediate or delayed complications as a result of the small degree of embolism. The locations of the emboli were in the subclavian or axillary vein in nine, right or left brachiocephalic vein in three, internal jugular vein in two, superior vena cava in two, right ventricle in two, and main pulmonary artery in 12 patients. In patients at high risk for cerebral air embolism, such as those with intracardiac shunts or pulmonary arteriovenous malformations, extreme caution should be used--even in the routine administration of intravenous fluids or contrast media--to prevent venous air embolism and resultant neurologic deficits.
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                Author and article information

                Journal
                Am J Case Rep
                Am J Case Rep
                amjcaserep
                The American Journal of Case Reports
                International Scientific Literature, Inc.
                1941-5923
                2017
                24 January 2017
                : 18
                : 80-84
                Affiliations
                Department of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, The University of Tennessee Health Science Center, Memphis, TN, U.S.A.
                Author notes

                Authors’ Contribution:

                [A]

                Study Design

                [B]

                Data Collection

                [C]

                Statistical Analysis

                [D]

                Data Interpretation

                [E]

                Manuscript Preparation

                [F]

                Literature Search

                [G]

                Funds Collection

                Conflict of interest: None declared

                Corresponding Author: Julio Lanfranco, e-mail: jlanfran@ 123456uthsc.edu
                Article
                901098
                10.12659/AJCR.901098
                5282968
                28115731
                207a2888-5d4b-4dd7-b05a-b16d4327a90a
                © Am J Case Rep, 2017

                This work is licensed under Creative Common Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0)

                History
                : 17 August 2016
                : 18 October 2016
                Categories
                Articles

                anoxia,embolism, air,hyperbaric oxygenation
                anoxia, embolism, air, hyperbaric oxygenation

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