32
views
0
recommends
+1 Recommend
0 collections
    2
    shares
      • Record: found
      • Abstract: found
      • Article: not found

      Liver regeneration: from myth to mechanism.

      Nature reviews. Molecular cell biology

      Animals, Cell Cycle, physiology, Cytokines, metabolism, DNA-Binding Proteins, Gene Expression Regulation, Growth Substances, Hepatectomy, Humans, Interleukin-6, Liver, pathology, Liver Regeneration, STAT3 Transcription Factor, Signal Transduction, Trans-Activators

      Read this article at

      ScienceOpenPublisherPubMed
      Bookmark
          There is no author summary for this article yet. Authors can add summaries to their articles on ScienceOpen to make them more accessible to a non-specialist audience.

          Abstract

          The unusual regenerative properties of the liver are a logical adaptation by organisms, as the liver is the main detoxifying organ of the body and is likely to be injured by ingested toxins. The numerous cytokine- and growth-factor-mediated pathways that are involved in regulating liver regeneration are being successfully dissected using molecular and genetic approaches. So what is known about this process at present and which questions remain?

          Related collections

          Author and article information

          Journal
          15459664
          10.1038/nrm1489

          Comments

          Comment on this article