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      Hydroxyapatite and Fluorapatite in Conservative Dentistry and Oral Implantology—A Review

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      Materials
      MDPI
      hydroxyapatite, fluorapatite, dentistry, calcium phosphates

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          Abstract

          Calcium phosphate, due to its similarity to the inorganic fraction of mineralized tissues, has played a key role in many areas of medicine, in particular, regenerative medicine and orthopedics. It has also found application in conservative dentistry and dental surgery, in particular, as components of toothpaste and mouth rinse, coatings of dental implants, cements, and bone substitute materials for the restoration of cavities in maxillofacial surgery. In dental applications, the most important role is played by hydroxyapatite and fluorapatite, i.e., calcium phosphates characterized by the highest chemical stability and very low solubility. This paper presents the role of both apatites in dentistry and a review of recent achievements in the field of the application of these materials.

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          Most cited references91

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          Surface treatments of titanium dental implants for rapid osseointegration.

          The osseointegration rate of titanium dental implants is related to their composition and surface roughness. Rough-surfaced implants favor both bone anchoring and biomechanical stability. Osteoconductive calcium phosphate coatings promote bone healing and apposition, leading to the rapid biological fixation of implants. The different methods used for increasing surface roughness or applying osteoconductive coatings to titanium dental implants are reviewed. Surface treatments, such as titanium plasma-spraying, grit-blasting, acid-etching, anodization or calcium phosphate coatings, and their corresponding surface morphologies and properties are described. Most of these surfaces are commercially available and have proven clinical efficacy (>95% over 5 years). The precise role of surface chemistry and topography on the early events in dental implant osseointegration remain poorly understood. In addition, comparative clinical studies with different implant surfaces are rarely performed. The future of dental implantology should aim to develop surfaces with controlled and standardized topography or chemistry. This approach will be the only way to understand the interactions between proteins, cells and tissues, and implant surfaces. The local release of bone stimulating or resorptive drugs in the peri-implant region may also respond to difficult clinical situations with poor bone quality and quantity. These therapeutic strategies should ultimately enhance the osseointegration process of dental implants for their immediate loading and long-term success.
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            Biological materials: Structure and mechanical properties

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              Calcium phosphate-based osteoinductive materials.

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                Author and article information

                Journal
                Materials (Basel)
                Materials (Basel)
                materials
                Materials
                MDPI
                1996-1944
                22 August 2019
                September 2019
                : 12
                : 17
                : 2683
                Affiliations
                Analytical Group, Department of Analytical Chemistry and Biomaterials, Faculty of Pharmacy with Laboratory Medicine Division, Medical University of Warsaw, 02-097 Warsaw, Poland
                Author notes
                Author information
                https://orcid.org/0000-0003-1985-0876
                https://orcid.org/0000-0002-4417-5836
                Article
                materials-12-02683
                10.3390/ma12172683
                6747619
                31443429
                20f073d6-0f00-4b5a-973e-df2ae9de884a
                © 2019 by the authors.

                Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license ( http://creativecommons.org/licenses/by/4.0/).

                History
                : 29 July 2019
                : 20 August 2019
                Categories
                Review

                hydroxyapatite,fluorapatite,dentistry,calcium phosphates

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