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      Introducing Hann windows for reducing edge-effects in patch-based image segmentation

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      PLoS ONE
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          Abstract

          There is a limitation in the size of an image that can be processed using computationally demanding methods such as e.g. Convolutional Neural Networks (CNNs). Furthermore, many networks are designed to work with a pre-determined fixed image size. Some imaging modalities—notably biological and medical—can result in images up to a few gigapixels in size, meaning that they have to be divided into smaller parts, or patches, for processing. However, when performing pixel classification, this may lead to undesirable artefacts, such as edge effects in the final re-combined image. We introduce windowing methods from signal processing to effectively reduce such edge effects. With the assumption that the central part of an image patch often holds richer contextual information than its sides and corners, we reconstruct the prediction by overlapping patches that are being weighted depending on 2-dimensional windows. We compare the results of simple averaging and four different windows: Hann, Bartlett-Hann, Triangular and a recently proposed window by Cui et al., and show that the cosine-based Hann window achieves the best improvement as measured by the Structural Similarity Index (SSIM). We also apply the Dice score to show that classification errors close to patch edges are reduced. The proposed windowing method can be used together with any CNN model for segmentation without any modification and significantly improves network predictions.

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                Author and article information

                Contributors
                Role: ConceptualizationRole: Formal analysisRole: InvestigationRole: MethodologyRole: SoftwareRole: VisualizationRole: Writing – original draftRole: Writing – review & editing
                Role: Funding acquisitionRole: InvestigationRole: MethodologyRole: Project administrationRole: ResourcesRole: SupervisionRole: ValidationRole: Writing – original draftRole: Writing – review & editing
                Role: Editor
                Journal
                PLoS One
                PLoS ONE
                plos
                plosone
                PLoS ONE
                Public Library of Science (San Francisco, CA USA )
                1932-6203
                2020
                12 March 2020
                : 15
                : 3
                : e0229839
                Affiliations
                [1 ] Department of IT, Uppsala University, Uppsala, Sweden
                [2 ] BioImage Informatics Facility of SciLifeLab, Uppsala, Sweden
                Newcastle University, UNITED KINGDOM
                Author notes

                Competing Interests: The authors have declared that no competing interests exist.

                Author information
                http://orcid.org/0000-0001-8182-0091
                http://orcid.org/0000-0002-4139-7003
                Article
                PONE-D-19-29003
                10.1371/journal.pone.0229839
                7067425
                32163435
                210e7d53-426f-436c-b912-d567233cfa6d
                © 2020 Pielawski, Wählby

                This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

                History
                : 18 October 2019
                : 14 February 2020
                Page count
                Figures: 5, Tables: 0, Pages: 11
                Funding
                Funded by: Stiftelsen för Strategisk Forskning (SE)
                Award ID: BD150008
                Award Recipient :
                Funded by: European Research Council
                Award ID: ERC-2015-CoG 683810
                Award Recipient :
                Funded by: Stiftelsen för Strategisk Forskning (SE)
                Award ID: SB16-0046
                Award Recipient :
                This project was financially supported by the Swedish Foundation for Strategic Research (grant SB16-0046 and BD150008) and the European Research Council (ERC-2015-CoG 683810). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
                Categories
                Research Article
                Research and Analysis Methods
                Imaging Techniques
                Computer and Information Sciences
                Neural Networks
                Biology and Life Sciences
                Neuroscience
                Neural Networks
                Biology and Life Sciences
                Neuroscience
                Cognitive Science
                Cognition
                Memory
                Biology and Life Sciences
                Neuroscience
                Learning and Memory
                Memory
                Engineering and Technology
                Digital Imaging
                Physical Sciences
                Mathematics
                Optimization
                Computer and Information Sciences
                Artificial Intelligence
                Machine Learning
                Deep Learning
                Social Sciences
                Linguistics
                Semantics
                Research and Analysis Methods
                Mathematical and Statistical Techniques
                Mathematical Functions
                Curve Fitting
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