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      Multiscale Entropy Analysis of Heart Rate Variability for Assessing the Severity of Sleep Disordered Breathing

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      Entropy
      MDPI AG

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          Physiological time-series analysis using approximate entropy and sample entropy.

          Entropy, as it relates to dynamical systems, is the rate of information production. Methods for estimation of the entropy of a system represented by a time series are not, however, well suited to analysis of the short and noisy data sets encountered in cardiovascular and other biological studies. Pincus introduced approximate entropy (ApEn), a set of measures of system complexity closely related to entropy, which is easily applied to clinical cardiovascular and other time series. ApEn statistics, however, lead to inconsistent results. We have developed a new and related complexity measure, sample entropy (SampEn), and have compared ApEn and SampEn by using them to analyze sets of random numbers with known probabilistic character. We have also evaluated cross-ApEn and cross-SampEn, which use cardiovascular data sets to measure the similarity of two distinct time series. SampEn agreed with theory much more closely than ApEn over a broad range of conditions. The improved accuracy of SampEn statistics should make them useful in the study of experimental clinical cardiovascular and other biological time series.
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            Heart Rate Variability : Standards of Measurement, Physiological Interpretation, and Clinical Use

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              Multiscale entropy analysis of biological signals

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                Author and article information

                Journal
                ENTRFG
                Entropy
                Entropy
                MDPI AG
                1099-4300
                January 2015
                January 12 2015
                : 17
                : 1
                : 231-243
                Article
                10.3390/e17010231
                210f722f-e4b8-4dab-be83-947c4b57d73a
                © 2015

                https://creativecommons.org/licenses/by/4.0/

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