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      High Prevalence of Pancreatic Disease in Chronic Renal Failure

      Nephron

      S. Karger AG

      Corticosteroids, Azathioprine, Dialysis, Transplantation, Renal failure, Uremia, Enzymes, Parathormone, Pancreatitis, Inspissation

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          Abstract

          The prevalence of pancreatic disease was determined in 21 autopsied uremic patients who had died during the course of maintenance hemodialysis, as compared with 60 autopsied patients without kidney or pancreatic disease. Histologic criteria of pancreatic disease included. (1) duct ectasia; (2) periductal fibrosis; (3) ductular proliferation; (4) acinar ductalar metaplasia, and (5) interstitial inflammation or fibrosis. Significant pancreatic disease was present in 56% of the uremic patients and only 11.8% of the controls (p < 0.01). Two uremic patients had abscesses in the tail of the pancreas. The clinical significance of the high prevalence of pancreatic pathologic alterations in uremia remains to be assessed.

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          Author and article information

          Journal
          NEF
          Nephron
          10.1159/issn.1660-8151
          Nephron
          S. Karger AG
          1660-8151
          2235-3186
          1977
          1977
          28 November 2008
          : 18
          : 1
          : 68-71
          Affiliations
          Division of Nephrology, Department of Medicine, Long Island College Hospital, Brooklyn, N.Y.
          Article
          180768 Nephron 1977;18:68–71
          10.1159/000180768
          846627
          © 1977 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          Page count
          Pages: 4
          Categories
          Original Paper

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