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      Outpatient Parenteral Antimicrobial Therapy Plus Buprenorphine for Opioid Use Disorder and Severe Injection-related Infections

      brief-report

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          Abstract

          In a pilot randomized trial in persons with opioid use disorder hospitalized with injection-related infections, an innovative care model combining outpatient parenteral antimicrobial therapy with buprenorphine treatment had similar clinical and drug use outcomes to usual care (inpatient intravenous antibiotic completion) and shortened hospital length of stay by 23.5 days.

          Clinical Trials Registration

          NCT03048643.

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          Author and article information

          Journal
          Clin Infect Dis
          Clin Infect Dis
          cid
          Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
          Oxford University Press (US )
          1058-4838
          1537-6591
          15 March 2020
          18 July 2019
          18 July 2020
          : 70
          : 6
          : 1226-1229
          Affiliations
          [1 ] Division of Infectious Disease, Center on Drug and Alcohol Research, University of Kentucky , Lexington
          [2 ] Center on Drug and Alcohol Research, University of Kentucky , Lexington
          [3 ] Division of Infectious Disease, University of Kentucky , Lexington
          Author notes
          Correspondence: L. C. Fanucchi, Division of Infectious Disease, Center on Drug and Alcohol Research, University of Kentucky, 845 Angliana Ave., Lexington, KY 40508 ( laura.fanucchi@ 123456uky.edu ).
          Author information
          http://orcid.org/0000-0003-0582-2399
          Article
          PMC7931831 PMC7931831 7931831 ciz654
          10.1093/cid/ciz654
          7931831
          31342057
          213c1973-e3cb-48a0-b788-6a810e3778fe
          © The Author(s) 2019. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.

          This article is published and distributed under the terms of the Oxford University Press, Standard Journals Publication Model ( https://academic.oup.com/journals/pages/open_access/funder_policies/chorus/standard_publication_model)

          History
          : 25 March 2019
          : 12 July 2019
          Page count
          Pages: 4
          Funding
          Funded by: National Institutes of Health, DOI 10.13039/100000002;
          Funded by: National Center for Advancing Translational Sciences, DOI 10.13039/100006108;
          Award ID: UL1TR001998
          Categories
          Brief Reports

          injection-drug use,antibiotics,buprenorphine,opioid-related disorders,endocarditis

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