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      A Pilot RCT of Psychodynamic Group Art Therapy for Patients in Acute Psychotic Episodes: Feasibility, Impact on Symptoms and Mentalising Capacity

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          Abstract

          This pilot study aimed to evaluate the feasibility of an assessor-blind, randomised controlled trial of psychodynamic art therapy for the treatment of patients with schizophrenia, and to generate preliminary data on the efficacy of this intervention during acute psychotic episodes. Fifty-eight inpatients with DSM-diagnoses of schizophrenia were randomised to either 12 twice-weekly sessions of psychodynamic group art therapy plus treatment as usual or to standard treatment alone. Primary outcome criteria were positive and negative psychotic and depressive symptoms as well as global assessment of functioning. Secondary outcomes were mentalising function, estimated with the Reading the mind in the eyes test and the Levels of emotional awareness scale, self-efficacy, locus of control, quality of life and satisfaction with care. Assessments were made at baseline, at post-treatment and at 12 weeks' follow-up. At 12 weeks, 55% of patients randomised to art therapy, and 66% of patients receiving treatment as usual were examined. In the per-protocol sample, art therapy was associated with a significantly greater mean reduction of positive symptoms and improved psychosocial functioning at post-treatment and follow-up, and with a greater mean reduction of negative symptoms at follow-up compared to standard treatment. The significant reduction of positive symptoms at post-treatment was maintained in an attempted intention-to-treat analysis. There were no group differences regarding depressive symptoms. Of secondary outcome parameters, patients in the art therapy group showed a significant improvement in levels of emotional awareness, and particularly in their ability to reflect about others' emotional mental states. This is one of the first randomised controlled trials on psychodynamic group art therapy for patients with acute psychotic episodes receiving hospital treatment. Results prove the feasibility of trials on art therapy during acute psychotic episodes and justify further research to substantiate preliminary positive results regarding symptom reduction and the recovery of mentalising function.

          Trial Registration

          ClinicalTrials.gov NCT01622166

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          Most cited references34

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          Post-randomisation exclusions: the intention to treat principle and excluding patients from analysis.

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            Reading literary fiction improves theory of mind.

            Understanding others' mental states is a crucial skill that enables the complex social relationships that characterize human societies. Yet little research has investigated what fosters this skill, which is known as Theory of Mind (ToM), in adults. We present five experiments showing that reading literary fiction led to better performance on tests of affective ToM (experiments 1 to 5) and cognitive ToM (experiments 4 and 5) compared with reading nonfiction (experiments 1), popular fiction (experiments 2 to 5), or nothing at all (experiments 2 and 5). Specifically, these results show that reading literary fiction temporarily enhances ToM. More broadly, they suggest that ToM may be influenced by engagement with works of art.
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              Multiple choice vocabulary test MWT as a valid and short test to estimate premorbid intelligence.

              The discrepancy between current and premorbid ability is a relevant indicator of acquired mental impairment, which itself is closely related to general cerebral dysfunction. The use of tests sensitive to cerebral dysfunction, raises relatively few problems compared with tests being resistant that are used to estimate premorbid mental ability. For premorbid ability, verbal tests assessing knowledge, especially vocabulary, have been shown to be valid. A test, possibly more insensitive to brain dysfunction than the ones usually administered, is the multiple choice vocabulary test (MWT = Mehrfachwahl-Wortschatz-Test). At present only German versions are available. They are presented in some detail because of their advantages. Construction of the MWT is simple, and it can be easily administered in about five minutes. The results correlate fairly well with global IQ in healthy adults (median of r = 0.72 in 22 samples) and are more insensitive to current disturbances than such tests as the WAIS vocabulary test. The limitations of premorbid tests with respect to diagnostic validity are discussed. It is concluded, that studies which do not control premorbid intelligence have to be considered as a "malpractice" and should not be accepted by scientists.
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                Author and article information

                Contributors
                Role: Editor
                Journal
                PLoS One
                PLoS ONE
                plos
                plosone
                PLoS ONE
                Public Library of Science (San Francisco, USA )
                1932-6203
                2014
                13 November 2014
                : 9
                : 11
                : e112348
                Affiliations
                [1 ]Charité University Medicine Berlin (Charité Universitätsmedizin Berlin), Department of Psychiatry and Psychotherapy, Campus Mitte, Berlin, Germany
                [2 ]Weissensee School of Art (Kunsthochschule Berlin-Weißensee), Art Therapy Department, Berlin, Germany
                Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, China
                Author notes

                Competing Interests: The authors have declared that no competing interests exist.

                Conceived and designed the experiments: CM MB LH DS UH KD JG. Performed the experiments: LH CM MB. Analyzed the data: CM. Contributed reagents/materials/analysis tools: DS UH KD MB. Wrote the paper: CM LH DS KD. Performed art therapy: DS. Supervised art therapist: UH KD.

                Article
                PONE-D-14-18864
                10.1371/journal.pone.0112348
                4231093
                25393414
                2141f7f0-d0be-4cd3-a3a8-775f3ef15521
                Copyright @ 2014

                This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

                History
                : 26 May 2014
                : 1 October 2014
                Page count
                Pages: 11
                Funding
                The study was financially supported by the Weissensee School of Art. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
                Categories
                Research Article
                Biology and Life Sciences
                Neuroscience
                Cognitive Neuroscience
                Cognitive Neurology
                Neuropsychological Testing
                Consciousness
                Self-Consciousness
                Cognitive Science
                Cognitive Psychology
                Social Cognition
                Behavioral Neuroscience
                Neuropsychology
                Medicine and Health Sciences
                Clinical Medicine
                Clinical Trials
                Clinical Trial Reporting
                Randomized Controlled Trials
                Mental Health and Psychiatry
                Mental Health Therapies
                Psychotherapy
                Psychoses
                Schizophrenia
                Custom metadata
                The authors confirm that all data underlying the findings are fully available without restriction. Due to an ethical restriction, data cannot be made publicly available. However, all data will be made available to all interested researchers after receiving permission from the data protection officials of the Charité Universitätsmedizin Berlin committee. Requests for data access will be received by Christiane Montag ( Christiane.Montag@ 123456charite.de ).

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                Uncategorized

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