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      Bulimia nervosa and alcohol dependence. A case report of a patient enrolled in a randomized controlled clinical trial.

      Journal of substance abuse treatment

      Adult, Alcoholism, complications, therapy, Antidepressive Agents, Second-Generation, administration & dosage, Bulimia, Cognitive Therapy, Female, Fluoxetine, Humans, Randomized Controlled Trials as Topic, Serotonin Uptake Inhibitors, Treatment Outcome

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          Abstract

          Bulimia nervosa and alcohol use disorders frequently co-occur. A review of the literature, however, reveals a paucity of information on treatment of patients with these comorbid conditions. We present a case report of a 34-year-old Caucasian female with a 20-year history of bulimia nervosa with co-occurring alcohol dependence, who participated in a randomized placebo-controlled medication augmentation trial for bulimia nervosa. The patient served as a pilot subject who met the exclusionary criterion of alcohol dependence, but received all the assessment and intervention procedures of the clinical trial for bulimia nervosa. Despite double-blind random assignment to a placebo condition, the patient's symptoms of bulimia nervosa substantially improved over the course of the 5-week efficacy trial. We hypothesize that this improvement was due to concurrent abstinence from alcohol rather than a placebo effect.

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