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      Postural Variations of Intraocular Pressure - Preflight Experiments for the D 1-Mission


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          Specific alterations in systemic circulation due to fluid shift in microgravity may lead to a rise in intraocular pressure (IOP). This situation can be simulated by head-down tilt. Several series of tonometry were performed using a handheld applanation tonometer: (1) Short time postural changes up to -90° head down and back. (2) A period of 2 h in -10° head down. (3) Repetition of series 2 after dehydration of the subjects. (4) Seven-day bedrest study in -7° head-down tilt. (5) A period of lower body negative pressure (LBNP). (6) Valsalva maneuver. Immediately on tilting, the IOP rises with hydrostatic pressure and returns to normal again after about 1 h. The IOP seems to change parallel to venous pressure. Further experiments are planned for Spacelab missions.

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          Author and article information

          Ophthalmic Res
          Ophthalmic Research
          S. Karger AG
          04 December 2009
          : 18
          : 1
          : 55-60
          Department of Ophthalmology, Hamburg University (Head: Prof. J. Draeger), Hamburg, FRG
          265415 Ophthalmic Res 1986;18:55–60
          © 1986 S. Karger AG, Basel

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          : 03 September 1984
          : 21 August 1985
          Page count
          Pages: 6
          Original Paper

          Vision sciences,Ophthalmology & Optometry,Pathology
          Lower body negative pressure,Hand-applanation tonometer,Intraocular pressure,Bedrest study,Head-down tilt,Valsalva maneuver


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