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      Postural Variations of Intraocular Pressure - Preflight Experiments for the D 1-Mission

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          Abstract

          Specific alterations in systemic circulation due to fluid shift in microgravity may lead to a rise in intraocular pressure (IOP). This situation can be simulated by head-down tilt. Several series of tonometry were performed using a handheld applanation tonometer: (1) Short time postural changes up to -90° head down and back. (2) A period of 2 h in -10° head down. (3) Repetition of series 2 after dehydration of the subjects. (4) Seven-day bedrest study in -7° head-down tilt. (5) A period of lower body negative pressure (LBNP). (6) Valsalva maneuver. Immediately on tilting, the IOP rises with hydrostatic pressure and returns to normal again after about 1 h. The IOP seems to change parallel to venous pressure. Further experiments are planned for Spacelab missions.

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          Author and article information

          Journal
          ORE
          Ophthalmic Res
          10.1159/issn.0030-3747
          Ophthalmic Research
          S. Karger AG
          0030-3747
          1423-0259
          1986
          1986
          04 December 2009
          : 18
          : 1
          : 55-60
          Affiliations
          Department of Ophthalmology, Hamburg University (Head: Prof. J. Draeger), Hamburg, FRG
          Article
          265415 Ophthalmic Res 1986;18:55–60
          10.1159/000265415
          3951805
          21cf23e0-57ab-4317-8d10-3cb13fe30331
          © 1986 S. Karger AG, Basel

          Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher. Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug. Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.

          History
          : 03 September 1984
          : 21 August 1985
          Page count
          Pages: 6
          Categories
          Original Paper

          Vision sciences,Ophthalmology & Optometry,Pathology
          Lower body negative pressure,Hand-applanation tonometer,Intraocular pressure,Bedrest study,Head-down tilt,Valsalva maneuver

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