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      Applications of Deep Learning to Neuro-Imaging Techniques

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          Abstract

          Many clinical applications based on deep learning and pertaining to radiology have been proposed and studied in radiology for classification, risk assessment, segmentation tasks, diagnosis, prognosis, and even prediction of therapy responses. There are many other innovative applications of AI in various technical aspects of medical imaging, particularly applied to the acquisition of images, ranging from removing image artifacts, normalizing/harmonizing images, improving image quality, lowering radiation and contrast dose, and shortening the duration of imaging studies. This article will address this topic and will seek to present an overview of deep learning applied to neuroimaging techniques.

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          A survey on deep learning in medical image analysis

          Deep learning algorithms, in particular convolutional networks, have rapidly become a methodology of choice for analyzing medical images. This paper reviews the major deep learning concepts pertinent to medical image analysis and summarizes over 300 contributions to the field, most of which appeared in the last year. We survey the use of deep learning for image classification, object detection, segmentation, registration, and other tasks. Concise overviews are provided of studies per application area: neuro, retinal, pulmonary, digital pathology, breast, cardiac, abdominal, musculoskeletal. We end with a summary of the current state-of-the-art, a critical discussion of open challenges and directions for future research.
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            Artificial intelligence in radiology

            Artificial intelligence (AI) algorithms, particularly deep learning, have demonstrated remarkable progress in image-recognition tasks. Methods ranging from convolutional neural networks to variational autoencoders have found myriad applications in the medical image analysis field, propelling it forward at a rapid pace. Historically, in radiology practice, trained physicians visually assessed medical images for the detection, characterization and monitoring of diseases. AI methods excel at automatically recognizing complex patterns in imaging data and providing quantitative, rather than qualitative, assessments of radiographic characteristics. In this O pinion article, we establish a general understanding of AI methods, particularly those pertaining to image-based tasks. We explore how these methods could impact multiple facets of radiology, with a general focus on applications in oncology, and demonstrate ways in which these methods are advancing the field. Finally, we discuss the challenges facing clinical implementation and provide our perspective on how the domain could be advanced.
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              Artificial intelligence in healthcare: past, present and future

              Artificial intelligence (AI) aims to mimic human cognitive functions. It is bringing a paradigm shift to healthcare, powered by increasing availability of healthcare data and rapid progress of analytics techniques. We survey the current status of AI applications in healthcare and discuss its future. AI can be applied to various types of healthcare data (structured and unstructured). Popular AI techniques include machine learning methods for structured data, such as the classical support vector machine and neural network, and the modern deep learning, as well as natural language processing for unstructured data. Major disease areas that use AI tools include cancer, neurology and cardiology. We then review in more details the AI applications in stroke, in the three major areas of early detection and diagnosis, treatment, as well as outcome prediction and prognosis evaluation. We conclude with discussion about pioneer AI systems, such as IBM Watson, and hurdles for real-life deployment of AI.
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                Author and article information

                Contributors
                Journal
                Front Neurol
                Front Neurol
                Front. Neurol.
                Frontiers in Neurology
                Frontiers Media S.A.
                1664-2295
                14 August 2019
                2019
                : 10
                : 869
                Affiliations
                Neuroradiology Section, Department of Radiology, Stanford Healthcare , Stanford, CA, United States
                Author notes

                Edited by: Hongyu An, Washington University in St. Louis, United States

                Reviewed by: Yann Quidé, University of New South Wales, Australia; Chia-Ling Phuah, Washington University School of Medicine in St. Louis, United States

                *Correspondence: Max Wintermark max.wintermark@ 123456gmail.com

                This article was submitted to Applied Neuroimaging, a section of the journal Frontiers in Neurology

                Article
                10.3389/fneur.2019.00869
                6702308
                31474928
                2204ebee-7b2a-4de9-bc82-39e0a2a17848
                Copyright © 2019 Zhu, Jiang, Tong, Xie, Zaharchuk and Wintermark.

                This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

                History
                : 13 March 2019
                : 26 July 2019
                Page count
                Figures: 6, Tables: 0, Equations: 0, References: 107, Pages: 13, Words: 9591
                Categories
                Neurology
                Review

                Neurology
                artificial intelligence,deep learning,radiology,neuro-imaging,acquisition
                Neurology
                artificial intelligence, deep learning, radiology, neuro-imaging, acquisition

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