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      Salvage with a Secondary Infrahepatic Cavocavostomy of the Occluded Modified Piggyback Anastomosis during Split Liver Transplantation: A Case Report

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          Abstract

          Hepatic venous outflow obstruction following liver transplantation is rare but disastrous. Here we described a 14-year-old boy who underwent a split right lobe liver transplantation with modified (side-to-side) piggyback technique which resulted in hepatic venous outflow obstruction. When the liver graft was lifted up, the outflow drainage returned to normal but when it was placed back into the abdomen, the outflow obstruction recurred. Because reanastomosis would have resulted in hepatic reischemia, alternatively, a second infrahepatic cavocavostomy was planned without requiring hepatic reischemia. During this procedure, the first assistant hung the liver up to provide sufficient outflow and the portal inflow of the graft continued as well. We only clamped the recipient's infrahepatic vena cava and the caudal cuff of the graft cava. After the second end-to-side cavocaval anastomosis, the graft was placed in its orthotopic position and there was no outflow problem anymore. The patient tolerated the procedure well and there were no problems after three months of follow-up. A second cavocavostomy can provide an extra bypass for some hepatic venous outflow problems after piggyback anastomosis by avoiding hepatic reischemia.

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          Most cited references10

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          Reconstruction of the hepatic vein in reduced size hepatic transplantation.

          Reconstruction of the hepatic vein (HV) is not required in size-matched orthotopic liver transplantation (OLT) because the vena cava (VC) is replaced. In reduced size OLT, used for providing small livers for children, the HV is often implanted directly. Grafts obtained from a split liver in which the right lobe is used for a second recipient or from a live donor must be implanted without the VC. To evaluate the occurrence of outflow complications and their prevention, we have reviewed our experience with 72 left sided reduced grafts in children. Between July 1985 and November 1990, 93 reduced grafts were performed. Twenty-one were right lobe grafts with orthotopic replacement of the VC. Seventy-two were left grafts comprising 28 full left lobes and 44 lateral segments. Grafts were obtained from reduction of a cadaver liver in 39, from the left lobe of a split liver in 21 and from a live donor in 12. Of the left grafts, 47 were implanted with preservation of the recipient VC. Overall, HV obstruction occurred in 12 patients. Obstruction occurred acutely in three patients, causing graft failure and death in two and was repaired successfully in one patient. Chronic HV obstruction was documented in three patients with ascites and graft enlargement requiring retransplantation. This complication occurred in five of 25 patients with VC, six of 18 with end to end HV anastomosis, one of 18 with end to side implantation of HV and zero of 15 using a triangular anastomosis (p = 0.05). Outflow obstruction has not received adequate attention in descriptions of reduced-size OLT. Marked hepatic swelling and fluid retention that occur after reduced size hepatic transplantation may be the result of incomplete HV obstruction. In this series, end to end anastomosis of the HV resulted in a high frequency of outflow obstruction. This was prevented when anastomoses were designed to allow the graft to rest comfortably in the hepatic fossa after abdominal closure.
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            Improving hepatic and portal venous flows using tissue expander and Foley catheter in liver transplantation.

            Vascular reconstruction is important in liver transplantation because its obstruction causes graft failure and eventual loss. Vascular outflow obstruction may be due to graft malposition. We describe our experience with liver allograft repositioning using tissue expander and Foley catheter to improve hepatic and portal venous outflows.
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              Side-to-side cavocavostomy with an endovascular stapler: Rescue technique for severe hepatic vein and/or inferior vena cava outflow obstruction after liver transplantation using the piggyback technique.

              Venous outflow obstruction is a rare but potentially lethal complication after orthotopic liver transplantation (OLT) with the "piggyback" technique. Therapeutic options include angioplasty with or without stent placement, surgical reconstruction of the venous anastomosis, and retransplantation. Surgical options are technically very challenging and the outcomes discouraging. We describe here two cases of venous outflow obstruction in recipients of piggyback liver grafts, one involving both the vena cava and hepatic veins and the other affecting only hepatic vein outflow. Both patients were treated successfully with side-to-side cavo-cavostomy using an endovascular (endo-GIA) stapler. This novel technique is fast and effective in resolving the outflow obstruction.
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                Author and article information

                Journal
                Case Rep Transplant
                Case Rep Transplant
                CRIT
                Case Reports in Transplantation
                Hindawi Publishing Corporation
                2090-6943
                2090-6951
                2014
                21 May 2014
                : 2014
                : 740802
                Affiliations
                1Inonu University, Liver Transplantation Institute, 44280 Malatya, Turkey
                2Istanbul Training and Research Hospital, Department of General Surgery, 34098 Istanbul, Turkey
                Author notes

                Academic Editor: Yasuhiko Sugawara

                Article
                10.1155/2014/740802
                4055404
                22099767-fe1e-439f-acb7-b08d14463eff
                Copyright © 2014 Erdem Kinaci et al.

                This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

                History
                : 27 February 2014
                : 8 May 2014
                : 8 May 2014
                Categories
                Case Report

                Transplantation
                Transplantation

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