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      Maintenance electroconvulsive therapy for aggression and self-injurious behavior in two adolescents with autism and catatonia.

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          Abstract

          Frequent aggression toward others and repetitive self-injurious behaviors (SIB) can be features of catatonia in patients with autism. Similar to catatonia secondary to other etiologies, catatonia associated with autism responds well to treatment with benzodiazepines and/or electroconvulsive therapy (ECT). The authors report here on two adolescent patients with autism who presented with severe aggression, one of whom also engaged in repetitive SIB. With ongoing treatment with maintenance ECT, dramatic reduction in aggression and SIB were noted, allowing both patients a reasonable quality of life in their own homes. Attempts to taper off ECT coincided with return of aggression symptoms, although not SIB.

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          Author and article information

          Journal
          J Neuropsychiatry Clin Neurosci
          The Journal of neuropsychiatry and clinical neurosciences
          1545-7222
          0895-0172
          2014
          : 26
          : 1
          Article
          1828807
          10.1176/appi.neuropsych.12110284
          24515677

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