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      Global research output on HIV/AIDS–related medication adherence from 1980 to 2017

      research-article
      Author(s):
      Publication date (Electronic):
      Journal: BMC Health Services Research
      Publisher: BioMed Central
      Keywords: Medication adherence, HIV, AIDS, Bibliometric analysis, VOSviewer, ArcGIS 10.1

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          Abstract

          Background

          “Human Immunodeficiency Virus (HIV)” and Acquired Immunodeficiency Syndrome (AIDS) are global health burden. Medication adherence in people living with HIV (PLWH) is a key element in reducing morbidity and mortality. Quantitative and qualitative assessment of research activity helps identify research gaps as well as efforts implemented to improve adherence behaviors in PLWH. The aim of the current study was to assess and analyze literature on HIV/AIDS–related medication adherence using bibliometric methods.

          Methods

          SciVerse Scopus was used to accomplish the purpose of the current study. The study period included all times up to 2017. The analysis was restricted to documents published in academic journals.

          Results

          Search strategy retrieved 3021 documents with an average of 32.5 citations per document, an h-index of 136, and an average of 4.4 authors per documents. The volume of literature on HIV/AIDS-related medication adherence constituted 1.3% of the overall HIV/AIDS literature. There was a significant ( p < 0.01; r = 0.9) correlation between the growth of publications in AIDS-related stigma and medication adherence. The regions of America (567.9) had the highest research output per one million infected people (567.9) followed by the European region (314.3), Western Pacific Region (70.7), Eastern Mediterranean region (31.4), South East Asia (34.0), and Africa (19.3). Geographical distribution of publications showed an active contribution of certain countries in the Southern and Eastern region of Sub-Saharan Africa. Harvard University (8.4%; n = 254) was the most active institution. The top cited documents focused on the impact of adherence on disease outcome and the impact of text messages on improving medication adherence.

          Conclusion

          Research on medication adherence in PLWH showed regional variations. International research collaboration with high burden regions such as Sub-Saharan Africa needs to be strengthened to achieve the global target of ending AIDS as a public health threat by 2030.

          Electronic supplementary material

          The online version of this article (10.1186/s12913-018-3568-x) contains supplementary material, which is available to authorized users.

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          Most cited references53

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          Guidance for conducting systematic scoping reviews.

          Micah D.J. Peters, Christina M Godfrey, Hanan Khalil … (2015)
          Reviews of primary research are becoming more common as evidence-based practice gains recognition as the benchmark for care, and the number of, and access to, primary research sources has grown. One of the newer review types is the 'scoping review'. In general, scoping reviews are commonly used for 'reconnaissance' - to clarify working definitions and conceptual boundaries of a topic or field. Scoping reviews are therefore particularly useful when a body of literature has not yet been comprehensively reviewed, or exhibits a complex or heterogeneous nature not amenable to a more precise systematic review of the evidence. While scoping reviews may be conducted to determine the value and probable scope of a full systematic review, they may also be undertaken as exercises in and of themselves to summarize and disseminate research findings, to identify research gaps, and to make recommendations for the future research. This article briefly introduces the reader to scoping reviews, how they are different to systematic reviews, and why they might be conducted. The methodology and guidance for the conduct of systematic scoping reviews outlined below was developed by members of the Joanna Briggs Institute and members of five Joanna Briggs Collaborating Centres.
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            HIV infection: epidemiology, pathogenesis, treatment, and prevention.

            Gary Maartens, Connie Celum, Sharon R. Lewin (2014)
            HIV prevalence is increasing worldwide because people on antiretroviral therapy are living longer, although new infections decreased from 3.3 million in 2002, to 2.3 million in 2012. Global AIDS-related deaths peaked at 2.3 million in 2005, and decreased to 1.6 million by 2012. An estimated 9.7 million people in low-income and middle-income countries had started antiretroviral therapy by 2012. New insights into the mechanisms of latent infection and the importance of reservoirs of infection might eventually lead to a cure. The role of immune activation in the pathogenesis of non-AIDS clinical events (major causes of morbidity and mortality in people on antiretroviral therapy) is receiving increased recognition. Breakthroughs in the prevention of HIV important to public health include male medical circumcision, antiretrovirals to prevent mother-to-child transmission, antiretroviral therapy in people with HIV to prevent transmission, and antiretrovirals for pre-exposure prophylaxis. Research into other prevention interventions, notably vaccines and vaginal microbicides, is in progress. Copyright © 2014 Elsevier Ltd. All rights reserved.
            Article 0 comments Cited 271 times – based on 0 reviews     Review now
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              Bibliometric methods: pitfalls and possibilities.

              Jeffrey J. Wallin (2005)
              Bibliometric studies are increasingly being used for research assessment. Bibliometric indicators are strongly methodology-dependent but for all of them, various types of data normalization are an indispensable requirement. Bibliometric studies have many pitfalls; technical skill, critical sense and a precise knowledge about the examined scientific domain are required to carry out and interpret bibliometric investigations correctly.
              Article 0 comments Cited 176 times – based on 0 reviews     Review now
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                Author and article information

                Contributors
                Waleed M. Sweileh: + 970-599-225906 , waleedsweileh@yahoo.com
                Journal
                Journal ID (nlm-ta): BMC Health Serv Res
                Journal ID (iso-abbrev): BMC Health Serv Res
                Title: BMC Health Services Research
                Publisher: BioMed Central (London )
                ISSN (Electronic): 1472-6963
                Publication date (Electronic): 10 October 2018
                Publication date PMC-release: 10 October 2018
                Publication date Collection: 2018
                Volume: 18
                Electronic Location Identifier: 765
                Affiliations
                ISNI 0000 0004 0631 5695, GRID grid.11942.3f, Department of Physiology, Pharmacology/Toxicology, Division of Biomedical Sciences, College of Medicine and Health Sciences, , An-Najah National University, ; Nablus, Palestine
                Article
                Publisher ID: 3568
                DOI: 10.1186/s12913-018-3568-x
                PMC ID: 6180611
                PubMed ID: 30305093
                SO-VID: 22de9da4-634b-43a0-8477-2cf391045471
                Copyright © © The Author(s). 2018
                License:

                Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License ( http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver ( http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

                History
                Date received : 5 April 2018
                Date accepted : 26 September 2018
                Categories
                Subject: Research Article
                Custom metadata
                issue-copyright-statement © The Author(s) 2018

                ScienceOpen disciplines: Health & Social care
                Keywords: medication adherence,hiv,aids,bibliometric analysis,vosviewer,arcgis 10.1
                Data availability:
                ScienceOpen disciplines: Health & Social care
                Keywords: medication adherence, hiv, aids, bibliometric analysis, vosviewer, arcgis 10.1

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