Structure Guided Design, Synthesis, and Biological Evaluation of Novel Benzosuberene Analogues as Inhibitors of Tubulin Polymerization

Niu, Haichan; Strecker, Tracy E.; Gerberich, Jeni L.; Campbell, James; Saha, Debabrata; Mondal, Deboprosad; Hamel, Ernest; Chaplin, David J; Mason, Ralph P.; Trawick, Mary Lynn; Pinney, Kevin G

doi:10.1021/acs.jmedchem.9b00551

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Structure Guided Design, Synthesis, and Biological Evaluation of Novel Benzosuberene Analogues as Inhibitors of Tubulin Polymerization

Author(s): Haichan Niu , Tracy E. Strecker , Jeni L. Gerberich , James Campbell , Debabrata Saha , Deboprosad Mondal , Ernest Hamel , David J. Chaplin , Ralph P. Mason , Mary Lynn Trawick , Kevin G. Pinney

Publication date Created: May 06 2019

Publication date (Electronic): May 06 2019

Journal: Journal of Medicinal Chemistry

Publisher: American Chemical Society (ACS)

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Title: Journal of Medicinal Chemistry

Abbreviated Title: J. Med. Chem.

Publisher: American Chemical Society (ACS)

ISSN (Print): 0022-2623

ISSN (Electronic): 1520-4804

Publication date Created: May 06 2019

Publication date (Electronic): May 06 2019

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DOI: 10.1021/acs.jmedchem.9b00551

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Self URI (article page): http://pubs.acs.org/doi/10.1021/acs.jmedchem.9b00551

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Structure Guided Design, Synthesis, and Biological Evaluation of Novel Benzosuberene Analogues as Inhibitors of Tubulin Polymerization

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