To evaluate the efficacy of excimer laser phototherapeutic keratectomy (PTK) in treating the Schnyder cristalline corneal dystrophy. We examined the members of three generations of a family affected by Schnyder crystalline dystrophy. Two patients with disabling visual acuity were treated with PTK. The best corrected visual acuity (BCVA) of the patient with the cristalline form of the dystrophy progressed from 20/70 to 20/25. The BCVA of the other patient affected by the sine crystals form of the Schnyder dystrophy progressed from 20/70 to 20/30. Excimer laser photokeratectomy is a valuable tool in treating the Schnyder cristalline form of corneal dystrophy.