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      Ausgewählte Kupfer-katalysierte Reaktionen für die Bildung von C-N-, C-O-, C-S- und C-C-Bindungen

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          The medicinal chemist's toolbox: an analysis of reactions used in the pursuit of drug candidates.

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            Aryl-aryl bond formation one century after the discovery of the Ullmann reaction.

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              Biaryl Phosphane Ligands in Palladium-Catalyzed Amination

              Palladium-catalyzed amination reactions of aryl halides have undergone rapid development in the last 12 years, largely driven by the implementation of new classes of ligands. Biaryl phosphanes have proven to provide especially active catalysts in this context. This Review discusses the application of these catalysts in C-N cross-coupling reactions in the synthesis of heterocycles and pharmaceuticals, in materials science, and in natural product synthesis.

                Author and article information

                Journal
                Angewandte Chemie
                Angew. Chem.
                Wiley
                00448249
                December 18 2017
                December 18 2017
                November 14 2017
                : 129
                : 51
                : 16352-16397
                Affiliations
                [1 ]State Key Laboratory of Bioorganic & Natural Products Chemistry, Shanghai Institute of Organic Chemistry; Chinese Academy of Sciences; 354 Fenglin Lu Shanghai 200032 China
                Article
                10.1002/ange.201701690
                231902ff-64bb-4628-9b0c-a3c6816dc147
                © 2017

                http://doi.wiley.com/10.1002/tdm_license_1.1

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