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      Interneuron cell types are fit to function.

      1 , 2
      Nature
      Springer Science and Business Media LLC

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          Abstract

          Understanding brain circuits begins with an appreciation of their component parts - the cells. Although GABAergic interneurons are a minority population within the brain, they are crucial for the control of inhibition. Determining the diversity of these interneurons has been a central goal of neurobiologists, but this amazing cell type has so far defied a generalized classification system. Interneuron complexity within the telencephalon could be simplified by viewing them as elaborations of a much more finite group of developmentally specified cardinal classes that become further specialized as they mature. Our perspective emphasizes that the ultimate goal is to dispense with classification criteria and directly define interneuron types by function.

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          Author and article information

          Journal
          Nature
          Nature
          Springer Science and Business Media LLC
          1476-4687
          0028-0836
          Jan 16 2014
          : 505
          : 7483
          Affiliations
          [1 ] Cold Spring Harbor Laboratory, Marks Building, New York 11724, USA.
          [2 ] NYU Langone Medical Center, First Avenue, Smilow Research Building, New York 10016, USA.
          Article
          nature12983 NIHMS592464
          10.1038/nature12983
          4349583
          24429630
          23c1b29c-9ea5-422d-afda-58eb5c0963eb
          History

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