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      Priapism due to chronic myelocytic leukemia

      case-report

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          Abstract

          Priapism is defined as a whole or partial penile erection that persists for more than 4 hours without stimulation. Hematologic disorders are a significant risk factor for ischemic priapism. Here, we report a case of priapism due to chronic myelocytic leukemia. This is rare considering that the epidemiology of priapism in hematologic malignancies includes only 1% of patients with chronic myelocytic leukemia. Priapism has a relatively high complication rate, and management generally focuses on prompt treatment. Hematologic screening should be performed to rule out the possibility of these disorders that could underlie priapism.

          Highlights

          • Priapism is defined as a penile erection persisting for more than 4 hours without stimulation.

          • Here, we report a case of priapism due to chronic myelocytic leukemia.

          • Priapism is a urological emergency, which must be treated as early as possible.

          • Hematologic screening should be performed to rule out the possibility of undiagnosed hematologic disorders.

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          Most cited references5

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          How I treat priapism.

          Priapism is a disorder of persistent penile erection unrelated to sexual interest or desire. This pathologic condition, specifically the ischemic variant, is often associated with devastating complications, notably erectile dysfunction. Because priapism demonstrates high prevalence in patients with hematologic disorders, most commonly sickle cell disease (SCD), there is significant concern for its sequelae in this affected population. Thus, timely diagnosis and management are critical for the prevention or at least reduction of cavernosal tissue ischemia and potential damage consequent to each episode. Current guidelines and management strategies focus primarily on reactive treatments. However, an increasing understanding of the molecular pathophysiology of SCD-associated priapism has led to the identification of new potential therapeutic targets. Future agents are being developed and explored for use in the prevention of priapism. © 2015 by The American Society of Hematology.
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            Priapism – A Rare Presentation in Chronic Myeloid Leukemia: Case Report

            Priapism is a complication rarely seen in leukemia. We report a 19-year-old man presented with persistent painful erection of penis for over 24 hours at home. The patient had underwent immediate irrigation and decompression of priapism by urologist at emergency services of the hospital. This approach resulted in a flaccid penis later. During hospitalization, peripheral blood smear and bone marrow aspiration confirmed the diagnosis of chronic myeloid leukemia.
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              Priapism secondary to chronic myeloid leukemia treated by a surgical cavernosa-corpus spongiosum shunt: Case report

              Priapism secondary to chronic myeloid leukemia (CML) is rarely observed in the clinic. Here, we present an 18-year-old patient with priapism for over 72 h due to hyperleukocytosis. Emergent interventions such as therapeutic aspiration and intracorporal injection of phenylephrine failed before a surgical corpora cavernosa-corpus spongiosum shunt was inserted to relieve symptoms. During hospitalization, bone marrow aspiration confirmed the diagnosis of CML.

                Author and article information

                Contributors
                Journal
                Urol Case Rep
                Urol Case Rep
                Urology Case Reports
                Elsevier
                2214-4420
                16 November 2021
                January 2022
                16 November 2021
                : 40
                : 101946
                Affiliations
                [a ]Division of Urology, Department of Surgery, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia
                [b ]Department of Surgery, Faculty of Medicine, Hasanuddin University, Makassar, Indonesia
                Author notes
                []Corresponding author. Division of Urology, Department of Surgery, Faculty of Medicine, Hasanuddin University, Jalan Perintis Kemerdekaan KM 11, Makassar, 90245, South Sulawesi, Makassar, Indonesia. syarifbakri@ 123456hotmail.com
                Article
                S2214-4420(21)00386-7 101946
                10.1016/j.eucr.2021.101946
                8607158
                34840959
                243b3adc-9f94-4f73-be6c-1f21e73e6693
                © 2021 The Authors. Published by Elsevier Inc.

                This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

                History
                : 27 October 2021
                : 13 November 2021
                Categories
                General Urology

                priapism,leukemia,hematologic disorders,bone marrow aspiration,winter procedure

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