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      Predictive accuracy of risk scales following self-harm: multicentre, prospective cohort study

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          Abstract

          Background

          Scales are widely used in psychiatric assessments following self-harm. Robust evidence for their diagnostic use is lacking.

          Aims

          To evaluate the performance of risk scales (Manchester Self-Harm Rule, ReACT Self-Harm Rule, SAD PERSONS scale, Modified SAD PERSONS scale, Barratt Impulsiveness Scale); and patient and clinician estimates of risk in identifying patients who repeat self-harm within 6 months.

          Method

          A multisite prospective cohort study was conducted of adults aged 18 years and over referred to liaison psychiatry services following self-harm. Scale a priori cut-offs were evaluated using diagnostic accuracy statistics. The area under the curve (AUC) was used to determine optimal cut-offs and compare global accuracy.

          Results

          In total, 483 episodes of self-harm were included in the study. The episode-based 6-month repetition rate was 30% ( n = 145). Sensitivity ranged from 1% (95% CI 0–5) for the SAD PERSONS scale, to 97% (95% CI 93–99) for the Manchester Self-Harm Rule. Positive predictive values ranged from 13% (95% CI 2–47) for the Modified SAD PERSONS Scale to 47% (95% CI 41–53) for the clinician assessment of risk. The AUC ranged from 0.55 (95% CI 0.50–0.61) for the SAD PERSONS scale to 0.74 (95% CI 0.69–0.79) for the clinician global scale. The remaining scales performed significantly worse than clinician and patient estimates of risk ( P<0.001).

          Conclusions

          Risk scales following self-harm have limited clinical utility and may waste valuable resources. Most scales performed no better than clinician or patient ratings of risk. Some performed considerably worse. Positive predictive values were modest. In line with national guidelines, risk scales should not be used to determine patient management or predict self-harm.

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          Most cited references53

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          Applied Logistic Regression

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            Fatal and non-fatal repetition of self-harm. Systematic review.

            Non-fatal self-harm frequently leads to non-fatal repetition and sometimes to suicide. We need to quantify these two outcomes of self-harm to help us to develop and test effective interventions. To estimate rates of fatal and non-fatal repetition of self-harm. A systematic review of published follow-up data, from observational and experimental studies. Four electronic databases were searched and 90 studies met the inclusion criteria. Eighty per cent of studies found were undertaken in Europe, over one-third in the UK. Median proportions for repetition 1 year later were: 16% non-fatal and 2% fatal; after more than 9 years, around 7% of patients had died by suicide. The UK studies found particularly low rates of subsequent suicide. After 1 year, non-fatal repetition rates are around 15%. The strong connection between self-harm and later suicide lies somewhere between 0.5% and 2% after 1 year and above 5% after 9 years. Suicide risk among self-harm patients is hundreds of times higher than in the general population.
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              Statistics review 13: Receiver operating characteristic curves

              This review introduces some commonly used methods for assessing the performance of a diagnostic test. The sensitivity, specificity and likelihood ratio of a test are discussed. The uses of the receiver operating characteristic curve and the area under the curve are explained.
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                Author and article information

                Journal
                Br J Psychiatry
                Br J Psychiatry
                bjprcpsych
                The British Journal of Psychiatry
                Royal College of Psychiatrists
                0007-1250
                1472-1465
                June 2017
                June 2017
                : 210
                : 6
                : 429-436
                Affiliations
                Leah Quinlivan, PhD, Jayne Cooper, PhD, Centre for Suicide Prevention, Manchester Academic Health Science Centre, University of Manchester, Manchester; Declan Meehan, RMN, Damien Longson, FRCPsych, Greater Manchester Mental Health and NHS Foundation Trust, Manchester; John Potokar, MRCPsych, Avon & Wiltshire Mental Health Foundation Trust, Bristol, University Hospitals Bristol, NHS Foundation Trust, Bristol and School of Social and Community Medicine, University of Bristol, Bristol; Tom Hulme, MSc, University Hospitals Bristol, NHS Foundation Trust, Bristol, Bristol; Jennifer Marsden, BA, Derbyshire Healthcare NHS Foundation Trust, Derby; Fiona Brand, RMN, Kezia Lange, MRCPsych, Oxford Health NHS Foundation Trust, Oxford; Elena Riseborough, RMN, Lisa Page, PhD, Sussex Partnership NHS Foundation Trust, Worthing; Chris Metcalfe, PhD, School of Social and Community Medicine, University of Bristol, Bristol; Linda Davies, Institute of Population Health, University of Manchester, Manchester; Rory O' Connor, PhD, Institute of Health and Wellbeing, University of Glasgow, Glasgow; Keith Hawton, DSc, Centre for Suicide Research, University Department of Psychiatry, Warneford Hospital, Oxford; David Gunnell, DSc, School of Social and Community Medicine, University of Bristol, Bristol; Nav Kapur, MBChB, MMedSci, MD, FRCPsych, Centre for Suicide Prevention, Manchester Academic Health Science Centre, University of Manchester, and Greater Manchester Mental Health NHS Foundation Trust, Manchester, UK
                Author notes
                Correspondence: Leah Quinlivan, Jean McFarlane Building, University of Manchester, Oxford Road, Manchester M13 9PL, UK. Email: leah.quinlivan@ 123456manchester.ac.uk
                Article
                10.1192/bjp.bp.116.189993
                5451643
                28302702
                246e57c6-0706-4781-8e46-392bc234f5f9
                © The Royal College of Psychiatrists 2017.

                This is an open access article distributed under the terms of the Creative Commons Attribution (CC BY) licence.

                History
                : 30 June 2016
                : 5 October 2016
                : 13 November 2016
                Funding
                Funded by: National Institute of Health Research (NIHR)
                Award ID: RP-PG-0610-10026
                Categories
                Papers

                Clinical Psychology & Psychiatry
                Clinical Psychology & Psychiatry

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