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Novel Approaches for the Use of Cardiac/Coronary Computed Tomography Angiography

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Recent developments in the novel imaging technology of cardiac computed tomography (CT) not only permit detailed assessment of cardiac anatomy but also provide insight into cardiovascular physiology. Foremost, coronary CT angiography (CCTA) enables direct noninvasive examination of both coronary artery stenoses and atherosclerotic plaque characteristics. Calculation of computational fluid dynamics by cardiac CT allows the noninvasive estimation of fractional flow reserve, which increases the diagnostic accuracy for detection of hemodynamically significant coronary artery disease. In addition, a combination of myocardial CT perfusion and CCTA can provide simultaneous anatomical and functional assessment of coronary artery disease. Finally, detailed anatomical evaluation of atrial, ventricular, and valvular anatomy provides diagnostic information and guidance for procedural planning, such as for transcatheter aortic valve replacement. The clinical applications of cardiac CT will be extended with the development of these novel modalities.

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Author and article information

1Dalio Institute of Cardiovascular Imaging, Department of Radiology, New York-Presbyterian Hospital and Weill Cornell Medicine, New York, NY, United States
2State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, Beijing, China
aHadi Mirhedayati Mirhedayati and Donghee Han contributed equally to this work.
Author notes
Correspondence: James K. Min, MD, FACC, Dalio Institute of Cardiovascular Imaging, New York-Presbyterian Hospital and the Weill Cornell Medicine, 413 E. 69th Street, Suite 108, New York, NY 10021, USA, Tel.: +1-646-9626192, E-mail:
Cardiovascular Innovations and Applications
Compuscript (Ireland)
March 2017
March 2017
: 2
: 1
: 111-123
Copyright © 2017 Cardiovascular Innovations and Applications

This is an open-access article distributed under the terms of the Creative Commons Attribution 4.0 Unported License (CC BY-NC 4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. See

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